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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS41 All Species: 22.12
Human Site: S340 Identified Species: 34.76
UniProt: P49754 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49754 NP_055211.2 854 98566 S340 R D Y H L E Y S E G E S L F Y
Chimpanzee Pan troglodytes XP_519057 852 98261 G340 Y H L E Y S E G E S L F Y I V
Rhesus Macaque Macaca mulatta XP_001101460 879 101397 S365 R D Y H L E Y S E G E S L F Y
Dog Lupus familis XP_533084 854 98472 S340 R D Y H L E Y S E G E S L F Y
Cat Felis silvestris
Mouse Mus musculus Q5KU39 853 98584 S339 R D Y H L E Y S E G E S L F Y
Rat Rattus norvegicus NP_001100825 745 86357 K292 Y V K E V S E K T E R E Y C A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512356 1286 146402 S771 R D Y R L E Y S E G E S L F Y
Chicken Gallus gallus NP_001012877 804 93396 L329 K K K Y E E A L M A A E I S Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691671 854 99073 S340 R D Y R L E H S E G E S L F Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036416 841 96907 I343 N D Y S L G G I I E E N R F Y
Honey Bee Apis mellifera XP_624100 842 97559 L341 N D Y H L D C L K E E N R F F
Nematode Worm Caenorhab. elegans Q19954 901 102561 E360 L Q S E D M I E S V K L S N H
Sea Urchin Strong. purpuratus XP_797006 789 90527 V331 R L N H K D L V K I R P M D V
Poplar Tree Populus trichocarpa XP_002313553 952 107269 F352 D A L P V H R F E H Y K A K D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93043 980 110260 E356 A L P V H G F E H Y K A K D Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.5 97.7 N.A. 97.1 83.3 N.A. 61.1 86.7 N.A. 82.1 N.A. 37.8 43 28.1 50.2
Protein Similarity: 100 99.7 96.2 99.3 N.A. 99.3 85.8 N.A. 63.4 90.9 N.A. 89.9 N.A. 58.2 65.4 50.5 69.2
P-Site Identity: 100 6.6 100 100 N.A. 100 0 N.A. 93.3 6.6 N.A. 86.6 N.A. 40 40 0 13.3
P-Site Similarity: 100 6.6 100 100 N.A. 100 6.6 N.A. 93.3 26.6 N.A. 93.3 N.A. 46.6 66.6 13.3 33.3
Percent
Protein Identity: 35.7 N.A. N.A. 34.6 N.A. N.A.
Protein Similarity: 54.5 N.A. N.A. 52.8 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 7 0 0 7 7 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % C
% Asp: 7 54 0 0 7 14 0 0 0 0 0 0 0 14 7 % D
% Glu: 0 0 0 20 7 47 14 14 54 20 54 14 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 7 0 0 0 7 0 54 7 % F
% Gly: 0 0 0 0 0 14 7 7 0 40 0 0 0 0 0 % G
% His: 0 7 0 40 7 7 7 0 7 7 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 7 7 7 7 0 0 7 7 0 % I
% Lys: 7 7 14 0 7 0 0 7 14 0 14 7 7 7 0 % K
% Leu: 7 14 14 0 54 0 7 14 0 0 7 7 40 0 0 % L
% Met: 0 0 0 0 0 7 0 0 7 0 0 0 7 0 0 % M
% Asn: 14 0 7 0 0 0 0 0 0 0 0 14 0 7 0 % N
% Pro: 0 0 7 7 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 47 0 0 14 0 0 7 0 0 0 14 0 14 0 0 % R
% Ser: 0 0 7 7 0 14 0 40 7 7 0 40 7 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % T
% Val: 0 7 0 7 14 0 0 7 0 7 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 0 54 7 7 0 34 0 0 7 7 0 14 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _