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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
22.12
Human Site:
S340
Identified Species:
34.76
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S340
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
Chimpanzee
Pan troglodytes
XP_519057
852
98261
G340
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
I
V
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S365
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
Dog
Lupus familis
XP_533084
854
98472
S340
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S339
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
Rat
Rattus norvegicus
NP_001100825
745
86357
K292
Y
V
K
E
V
S
E
K
T
E
R
E
Y
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
S771
R
D
Y
R
L
E
Y
S
E
G
E
S
L
F
Y
Chicken
Gallus gallus
NP_001012877
804
93396
L329
K
K
K
Y
E
E
A
L
M
A
A
E
I
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
S340
R
D
Y
R
L
E
H
S
E
G
E
S
L
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
I343
N
D
Y
S
L
G
G
I
I
E
E
N
R
F
Y
Honey Bee
Apis mellifera
XP_624100
842
97559
L341
N
D
Y
H
L
D
C
L
K
E
E
N
R
F
F
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
E360
L
Q
S
E
D
M
I
E
S
V
K
L
S
N
H
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
V331
R
L
N
H
K
D
L
V
K
I
R
P
M
D
V
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
F352
D
A
L
P
V
H
R
F
E
H
Y
K
A
K
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
E356
A
L
P
V
H
G
F
E
H
Y
K
A
K
D
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
93.3
6.6
N.A.
86.6
N.A.
40
40
0
13.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
6.6
N.A.
93.3
26.6
N.A.
93.3
N.A.
46.6
66.6
13.3
33.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
7
0
0
7
7
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% C
% Asp:
7
54
0
0
7
14
0
0
0
0
0
0
0
14
7
% D
% Glu:
0
0
0
20
7
47
14
14
54
20
54
14
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
7
0
54
7
% F
% Gly:
0
0
0
0
0
14
7
7
0
40
0
0
0
0
0
% G
% His:
0
7
0
40
7
7
7
0
7
7
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
7
7
7
0
0
7
7
0
% I
% Lys:
7
7
14
0
7
0
0
7
14
0
14
7
7
7
0
% K
% Leu:
7
14
14
0
54
0
7
14
0
0
7
7
40
0
0
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
0
% M
% Asn:
14
0
7
0
0
0
0
0
0
0
0
14
0
7
0
% N
% Pro:
0
0
7
7
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
47
0
0
14
0
0
7
0
0
0
14
0
14
0
0
% R
% Ser:
0
0
7
7
0
14
0
40
7
7
0
40
7
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
7
0
7
14
0
0
7
0
7
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
54
7
7
0
34
0
0
7
7
0
14
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _