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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
24.55
Human Site:
S491
Identified Species:
38.57
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S491
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Chimpanzee
Pan troglodytes
XP_519057
852
98261
S489
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S516
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Dog
Lupus familis
XP_533084
854
98472
S491
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S490
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Rat
Rattus norvegicus
NP_001100825
745
86357
L427
I
L
G
K
N
A
S
L
W
E
Y
E
V
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
S922
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
L
Chicken
Gallus gallus
NP_001012877
804
93396
A465
R
T
L
L
R
T
L
A
E
L
Y
T
Y
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
M491
P
G
E
L
Y
N
N
M
A
I
V
Q
A
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
G491
W
P
S
H
L
Y
D
G
L
A
V
I
N
A
I
Honey Bee
Apis mellifera
XP_624100
842
97559
A493
S
P
K
L
Y
K
V
A
A
V
V
N
G
V
L
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
S531
S
P
D
L
Y
M
T
S
F
I
I
D
R
T
Q
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
L469
D
Q
R
Y
D
K
A
L
A
I
Y
L
E
L
G
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
L530
P
P
V
I
Y
S
A
L
P
V
I
S
A
I
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
L533
P
R
S
V
Y
S
A
L
T
V
I
S
A
I
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
6.6
N.A.
73.3
N.A.
6.6
26.6
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
93.3
26.6
N.A.
80
N.A.
20
40
46.6
13.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
20
14
20
7
0
0
60
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
47
0
7
0
7
0
0
0
0
7
0
7
7
% D
% Glu:
0
0
7
0
0
0
0
0
7
7
0
7
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
47
7
0
0
0
0
7
0
0
0
0
7
0
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
0
0
0
0
60
20
7
0
14
7
% I
% Lys:
0
0
7
7
0
14
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
7
7
67
7
0
7
27
7
7
0
7
0
7
14
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
47
47
0
0
0
0
7
7
0
7
% N
% Pro:
60
27
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
47
0
0
14
% Q
% Arg:
7
7
7
0
7
0
0
0
0
0
0
0
7
0
34
% R
% Ser:
14
0
14
0
0
14
7
47
0
0
0
14
0
0
0
% S
% Thr:
0
7
0
0
0
7
7
0
7
0
0
7
0
7
0
% T
% Val:
0
0
7
7
0
0
7
0
40
20
60
0
7
54
0
% V
% Trp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
74
7
0
0
0
0
20
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _