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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
33.33
Human Site:
S579
Identified Species:
52.38
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S579
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Chimpanzee
Pan troglodytes
XP_519057
852
98261
S577
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S604
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Dog
Lupus familis
XP_533084
854
98472
S579
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S578
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Rat
Rattus norvegicus
NP_001100825
745
86357
L513
N
K
T
L
L
K
T
L
A
E
L
Y
T
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
S1010
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Chicken
Gallus gallus
NP_001012877
804
93396
L551
Q
H
V
Y
L
H
K
L
F
K
R
D
H
H
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
S579
L
D
N
E
D
K
I
S
M
D
K
V
V
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
T579
L
D
K
K
K
I
K
T
E
I
V
V
H
Q
L
Honey Bee
Apis mellifera
XP_624100
842
97559
S582
L
E
K
D
R
V
P
S
D
I
V
V
Q
K
L
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
E629
L
D
N
A
D
S
V
E
P
S
F
V
M
E
K
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
A555
N
E
G
K
D
F
H
A
M
Q
V
E
L
Y
A
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
S618
I
Q
N
K
D
L
I
S
P
P
D
V
V
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
P621
I
Q
N
R
D
L
I
P
P
S
E
V
V
P
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
6.6
N.A.
86.6
N.A.
20
20
40
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
20
N.A.
93.3
N.A.
40
40
60
46.6
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
7
74
0
0
0
7
7
7
7
0
0
7
% D
% Glu:
0
14
0
47
0
0
0
7
7
7
7
7
0
54
47
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
7
7
0
0
0
0
0
14
7
0
% H
% Ile:
14
0
0
0
0
7
60
0
40
14
0
0
0
0
0
% I
% Lys:
0
7
14
20
7
54
14
0
0
47
47
0
0
7
20
% K
% Leu:
67
0
0
7
14
14
0
14
0
0
7
0
7
0
14
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
0
7
0
0
% M
% Asn:
14
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
7
20
7
0
0
0
7
0
% P
% Gln:
7
14
0
0
0
0
0
0
0
7
0
0
7
7
7
% Q
% Arg:
0
0
0
7
7
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
60
0
14
0
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
7
7
0
0
0
0
7
0
0
% T
% Val:
0
0
7
0
0
7
7
0
0
0
20
80
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
7
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _