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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS41 All Species: 22.73
Human Site: S668 Identified Species: 35.71
UniProt: P49754 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49754 NP_055211.2 854 98566 S668 S R M G N S R S A L K M I M E
Chimpanzee Pan troglodytes XP_519057 852 98261 S666 S R M G N S R S A L K M I M E
Rhesus Macaque Macaca mulatta XP_001101460 879 101397 S693 S R M G N S R S A L K M I M E
Dog Lupus familis XP_533084 854 98472 S668 S R M G N S R S A L K M I M E
Cat Felis silvestris
Mouse Mus musculus Q5KU39 853 98584 S667 S R M G N S R S A L K M I M E
Rat Rattus norvegicus NP_001100825 745 86357 H594 E D R P E L Q H V Y L H K L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512356 1286 146402 S1100 S R M G N S R S A L K M I M E
Chicken Gallus gallus NP_001012877 804 93396 E635 Q D V D K A I E F A K E Q D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691671 854 99073 R668 S R M G N C R R A L Q M I M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036416 841 96907 A665 G C M G G V E A S E A L N I I
Honey Bee Apis mellifera XP_624100 842 97559 E668 G R I G N T S E A L A L M T R
Nematode Worm Caenorhab. elegans Q19954 901 102561 D716 A K S G N H Y D A V K M M V R
Sea Urchin Strong. purpuratus XP_797006 789 90527 L636 K E H D D V E L W G D L I D Y
Poplar Tree Populus trichocarpa XP_002313553 952 107269 K713 G R M G N S K K A L T V I I N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93043 980 110260 Q725 G R M G N A K Q A L A V I I N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.5 97.7 N.A. 97.1 83.3 N.A. 61.1 86.7 N.A. 82.1 N.A. 37.8 43 28.1 50.2
Protein Similarity: 100 99.7 96.2 99.3 N.A. 99.3 85.8 N.A. 63.4 90.9 N.A. 89.9 N.A. 58.2 65.4 50.5 69.2
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 6.6 N.A. 80 N.A. 13.3 33.3 33.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 26.6 N.A. 86.6 N.A. 40 60 66.6 20
Percent
Protein Identity: 35.7 N.A. N.A. 34.6 N.A. N.A.
Protein Similarity: 54.5 N.A. N.A. 52.8 N.A. N.A.
P-Site Identity: 53.3 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 73.3 N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 14 0 7 74 7 20 0 0 0 0 % A
% Cys: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 14 7 0 0 7 0 0 7 0 0 14 7 % D
% Glu: 7 7 0 0 7 0 14 14 0 7 0 7 0 0 47 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % F
% Gly: 27 0 0 80 7 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 7 0 0 7 0 7 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 0 0 0 7 0 0 0 0 0 67 20 7 % I
% Lys: 7 7 0 0 7 0 14 7 0 0 54 0 7 0 0 % K
% Leu: 0 0 0 0 0 7 0 7 0 67 7 20 0 7 0 % L
% Met: 0 0 67 0 0 0 0 0 0 0 0 54 14 47 0 % M
% Asn: 0 0 0 0 74 0 0 0 0 0 0 0 7 0 14 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 7 7 0 0 7 0 7 0 0 % Q
% Arg: 0 67 7 0 0 0 47 7 0 0 0 0 0 0 14 % R
% Ser: 47 0 7 0 0 47 7 40 7 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 7 0 0 7 0 % T
% Val: 0 0 7 0 0 14 0 0 7 7 0 14 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _