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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
27.88
Human Site:
S95
Identified Species:
43.81
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S95
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Chimpanzee
Pan troglodytes
XP_519057
852
98261
S95
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S120
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Dog
Lupus familis
XP_533084
854
98472
S95
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S94
N
Q
I
S
L
D
D
S
G
E
H
M
G
V
C
Rat
Rattus norvegicus
NP_001100825
745
86357
L57
M
T
V
H
D
K
F
L
A
L
G
T
H
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
S526
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Chicken
Gallus gallus
NP_001012877
804
93396
F94
V
R
S
H
F
K
Q
F
V
T
G
G
K
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
S95
N
Q
I
S
L
D
E
S
G
D
H
V
G
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
K97
N
N
I
D
V
D
H
K
G
E
Y
V
A
T
C
Honey Bee
Apis mellifera
XP_624100
842
97559
N94
N
Q
I
S
I
D
Q
N
G
D
F
I
A
S
C
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
V106
H
R
C
A
V
S
K
V
K
F
D
E
T
G
S
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
Y95
S
M
D
M
N
G
D
Y
L
A
S
C
S
D
D
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
E105
N
D
L
S
F
D
V
E
G
E
Y
I
G
S
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
E109
N
D
I
N
F
D
T
E
G
E
Y
I
G
S
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
100
0
N.A.
80
N.A.
40
46.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
13.3
N.A.
100
N.A.
60
80
33.3
13.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
7
0
0
14
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
74
% C
% Asp:
0
14
7
7
7
74
14
0
0
14
7
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
40
14
0
60
0
7
0
0
0
% E
% Phe:
0
0
0
0
20
0
7
7
0
7
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
74
0
14
7
60
7
7
% G
% His:
7
0
0
14
0
0
7
0
0
0
47
0
7
0
0
% H
% Ile:
0
0
67
0
7
0
0
0
0
0
0
20
0
7
0
% I
% Lys:
0
0
0
0
0
14
7
7
7
0
0
0
7
7
0
% K
% Leu:
0
0
7
0
47
0
0
7
7
7
0
0
0
0
7
% L
% Met:
7
7
0
7
0
0
0
0
0
0
0
40
0
0
0
% M
% Asn:
74
7
0
7
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
54
0
0
0
0
14
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
60
0
7
0
47
0
0
7
0
7
20
7
% S
% Thr:
0
7
0
0
0
0
7
0
0
7
0
7
7
7
0
% T
% Val:
7
0
7
0
14
0
7
7
7
0
0
14
0
40
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
20
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _