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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
22.42
Human Site:
T294
Identified Species:
35.24
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
T294
V
K
E
I
S
E
K
T
E
R
E
Y
C
A
R
Chimpanzee
Pan troglodytes
XP_519057
852
98261
T294
V
K
E
I
S
E
K
T
K
Y
C
A
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
T319
V
K
E
I
S
E
K
T
E
R
E
Y
C
A
R
Dog
Lupus familis
XP_533084
854
98472
T294
V
K
E
V
S
E
K
T
E
R
E
Y
C
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
T293
V
K
E
V
S
E
K
T
E
R
E
Y
C
A
R
Rat
Rattus norvegicus
NP_001100825
745
86357
H246
I
C
S
V
K
E
R
H
A
S
E
M
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
T725
V
K
E
I
L
E
K
T
E
R
E
F
C
A
R
Chicken
Gallus gallus
NP_001012877
804
93396
R283
G
F
Q
E
N
E
C
R
D
Y
H
L
E
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
M294
V
K
E
N
S
D
H
M
E
E
E
F
R
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
S297
L
G
F
R
K
E
K
S
S
C
F
K
A
L
R
Honey Bee
Apis mellifera
XP_624100
842
97559
D295
L
G
C
L
K
E
L
D
E
N
G
K
S
Q
R
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
F314
L
Q
L
E
G
E
D
F
D
D
C
A
S
V
I
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
G285
S
E
Y
E
S
D
E
G
V
F
Y
I
V
S
P
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
I306
S
L
V
V
L
A
Y
I
P
V
E
E
D
G
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
I310
V
I
L
A
Y
I
P
I
E
G
D
G
E
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
60
100
93.3
N.A.
93.3
13.3
N.A.
86.6
6.6
N.A.
46.6
N.A.
20
20
6.6
6.6
P-Site Similarity:
100
66.6
100
100
N.A.
100
33.3
N.A.
93.3
26.6
N.A.
60
N.A.
33.3
33.3
26.6
33.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
7
0
0
14
7
34
0
% A
% Cys:
0
7
7
0
0
0
7
0
0
7
14
0
34
0
0
% C
% Asp:
0
0
0
0
0
14
7
7
14
7
7
0
7
7
0
% D
% Glu:
0
7
47
20
0
74
7
0
54
7
54
7
14
0
14
% E
% Phe:
0
7
7
0
0
0
0
7
0
7
7
14
0
0
0
% F
% Gly:
7
14
0
0
7
0
0
7
0
7
7
7
0
7
0
% G
% His:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% H
% Ile:
7
7
0
27
0
7
0
14
0
0
0
7
0
0
7
% I
% Lys:
0
47
0
0
20
0
47
0
7
0
0
14
0
7
0
% K
% Leu:
20
7
14
7
14
0
7
0
0
0
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
7
0
0
0
0
7
7
% P
% Gln:
0
7
7
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
7
0
0
7
7
0
34
0
0
20
0
60
% R
% Ser:
14
0
7
0
47
0
0
7
7
7
0
0
14
7
7
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
0
0
7
0
% T
% Val:
54
0
7
27
0
0
0
0
7
7
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
7
0
0
14
7
27
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _