KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
25.76
Human Site:
Y286
Identified Species:
40.48
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
Y286
D
Q
L
V
V
L
S
Y
V
K
E
I
S
E
K
Chimpanzee
Pan troglodytes
XP_519057
852
98261
Y286
D
Q
L
V
V
L
S
Y
V
K
E
I
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
Y311
D
Q
L
V
V
L
S
Y
V
K
E
I
S
E
K
Dog
Lupus familis
XP_533084
854
98472
Y286
D
Q
L
V
V
L
S
Y
V
K
E
V
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
Y285
D
Q
L
V
V
L
S
Y
V
K
E
V
S
E
K
Rat
Rattus norvegicus
NP_001100825
745
86357
K238
I
G
W
G
T
S
I
K
I
C
S
V
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
Y717
D
Q
L
V
I
L
S
Y
V
K
E
I
L
E
K
Chicken
Gallus gallus
NP_001012877
804
93396
R275
S
S
D
A
L
T
V
R
G
F
Q
E
N
E
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
Y286
D
Q
L
V
T
L
Y
Y
V
K
E
N
S
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
V289
L
S
A
K
Q
L
V
V
L
G
F
R
K
E
K
Honey Bee
Apis mellifera
XP_624100
842
97559
L287
P
L
E
N
Q
L
V
L
L
G
C
L
K
E
L
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
G306
N
M
E
L
F
L
V
G
L
Q
L
E
G
E
D
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
V277
A
R
S
S
A
A
I
V
S
E
Y
E
S
D
E
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
D298
S
G
I
A
P
F
G
D
S
L
V
V
L
A
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
L302
I
A
P
F
G
D
S
L
V
I
L
A
Y
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
86.6
6.6
N.A.
66.6
N.A.
20
13.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
93.3
26.6
N.A.
73.3
N.A.
26.6
26.6
40
33.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
14
7
7
0
0
0
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
7
% C
% Asp:
47
0
7
0
0
7
0
7
0
0
0
0
0
14
7
% D
% Glu:
0
0
14
0
0
0
0
0
0
7
47
20
0
74
7
% E
% Phe:
0
0
0
7
7
7
0
0
0
7
7
0
0
0
0
% F
% Gly:
0
14
0
7
7
0
7
7
7
14
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
14
0
7
0
7
0
14
0
7
7
0
27
0
7
0
% I
% Lys:
0
0
0
7
0
0
0
7
0
47
0
0
20
0
47
% K
% Leu:
7
7
47
7
7
67
0
14
20
7
14
7
14
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
0
0
0
7
7
0
0
% N
% Pro:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
47
0
0
14
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
7
0
0
0
7
0
0
7
% R
% Ser:
14
14
7
7
0
7
47
0
14
0
7
0
47
0
0
% S
% Thr:
0
0
0
0
14
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
47
34
0
27
14
54
0
7
27
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
47
0
0
7
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _