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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS41 All Species: 32.12
Human Site: Y411 Identified Species: 50.48
UniProt: P49754 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49754 NP_055211.2 854 98566 Y411 H L V E R G D Y D I A A R K C
Chimpanzee Pan troglodytes XP_519057 852 98261 Y409 H L V E R G D Y D I A A R K C
Rhesus Macaque Macaca mulatta XP_001101460 879 101397 Y436 H L V E R G D Y D I A A R K C
Dog Lupus familis XP_533084 854 98472 Y411 H L V E K G D Y D I A A R K C
Cat Felis silvestris
Mouse Mus musculus Q5KU39 853 98584 Y410 H L V E R G E Y D M A A R K C
Rat Rattus norvegicus NP_001100825 745 86357 D352 F Y V V S P R D V V V A K E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512356 1286 146402 H842 H L V E K G E H D L A A R K C
Chicken Gallus gallus NP_001012877 804 93396 I389 E V Y K F K E I G Q L K A I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691671 854 99073 Y411 H L V E K G D Y D T A A R K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036416 841 96907 Y411 H L L A L K K Y D D A A K L C
Honey Bee Apis mellifera XP_624100 842 97559 Y413 H L L A C G K Y D E A G K L C
Nematode Worm Caenorhab. elegans Q19954 901 102561 A451 G Y L T G K R A R A A A S R L
Sea Urchin Strong. purpuratus XP_797006 789 90527 P391 K V I S Q Y I P K G D M R L S
Poplar Tree Populus trichocarpa XP_002313553 952 107269 Y448 H L I V E R K Y G E A A S L C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93043 980 110260 Y451 H L I V E R K Y A E A A S L C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.5 97.7 N.A. 97.1 83.3 N.A. 61.1 86.7 N.A. 82.1 N.A. 37.8 43 28.1 50.2
Protein Similarity: 100 99.7 96.2 99.3 N.A. 99.3 85.8 N.A. 63.4 90.9 N.A. 89.9 N.A. 58.2 65.4 50.5 69.2
P-Site Identity: 100 100 100 93.3 N.A. 86.6 13.3 N.A. 73.3 0 N.A. 86.6 N.A. 46.6 46.6 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 100 20 N.A. 93.3 N.A. 60 60 26.6 26.6
Percent
Protein Identity: 35.7 N.A. N.A. 34.6 N.A. N.A.
Protein Similarity: 54.5 N.A. N.A. 52.8 N.A. N.A.
P-Site Identity: 40 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 0 0 7 7 7 80 80 7 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 74 % C
% Asp: 0 0 0 0 0 0 34 7 60 7 7 0 0 0 0 % D
% Glu: 7 0 0 47 14 0 20 0 0 20 0 0 0 7 0 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 7 54 0 0 14 7 0 7 0 0 0 % G
% His: 74 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 7 7 0 27 0 0 0 7 0 % I
% Lys: 7 0 0 7 20 20 27 0 7 0 0 7 20 47 0 % K
% Leu: 0 74 20 0 7 0 0 0 0 7 7 0 0 34 7 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 27 14 14 0 7 0 0 0 54 7 7 % R
% Ser: 0 0 0 7 7 0 0 0 0 0 0 0 20 0 14 % S
% Thr: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 14 54 20 0 0 0 0 7 7 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 14 7 0 0 7 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _