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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
30.3
Human Site:
Y434
Identified Species:
47.62
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
Y434
A
L
W
E
Y
E
V
Y
K
F
K
E
I
G
Q
Chimpanzee
Pan troglodytes
XP_519057
852
98261
Y432
A
L
W
E
Y
E
V
Y
K
F
K
E
I
G
Q
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
Y459
A
L
W
E
Y
E
V
Y
K
F
K
E
I
G
Q
Dog
Lupus familis
XP_533084
854
98472
Y434
A
L
W
E
C
E
V
Y
K
F
K
E
I
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
Y433
S
L
W
E
Y
E
V
Y
K
F
K
E
I
G
Q
Rat
Rattus norvegicus
NP_001100825
745
86357
E370
D
H
I
D
W
L
L
E
K
K
K
Y
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
Y865
A
L
W
E
C
E
V
Y
K
F
K
E
I
G
Q
Chicken
Gallus gallus
NP_001012877
804
93396
P408
R
R
D
P
V
L
K
P
L
I
Y
E
M
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
Y434
D
L
W
E
N
E
V
Y
R
F
K
T
I
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
F434
V
L
W
E
E
E
V
F
K
F
V
K
C
Q
Q
Honey Bee
Apis mellifera
XP_624100
842
97559
Y436
K
L
W
E
E
E
V
Y
K
F
A
R
V
H
Q
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
N474
E
E
W
E
W
A
V
N
Q
F
E
E
V
K
L
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
T412
I
L
N
E
Y
L
Q
T
D
L
Q
G
F
N
K
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
F473
W
E
R
W
V
F
H
F
A
H
L
R
Q
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
F476
W
E
R
W
V
F
H
F
A
Q
L
R
Q
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
93.3
6.6
N.A.
73.3
N.A.
53.3
60
33.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
93.3
13.3
N.A.
80
N.A.
66.6
66.6
60
33.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
7
0
0
14
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
14
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
14
0
7
7
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
7
20
0
74
14
60
0
7
0
0
7
54
7
7
0
% E
% Phe:
0
0
0
0
0
14
0
20
0
67
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
0
47
0
% G
% His:
0
7
0
0
0
0
14
0
0
7
0
0
0
7
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
7
0
0
47
0
0
% I
% Lys:
7
0
0
0
0
0
7
0
60
7
54
7
0
7
7
% K
% Leu:
0
67
0
0
0
20
7
0
7
7
14
0
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
7
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
14
% P
% Gln:
0
0
0
0
0
0
7
0
7
7
7
0
14
7
60
% Q
% Arg:
7
7
14
0
0
0
0
0
7
0
0
20
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% T
% Val:
7
0
0
0
20
0
67
0
0
0
7
0
14
7
0
% V
% Trp:
14
0
67
14
14
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
0
0
54
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _