KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
27.27
Human Site:
Y473
Identified Species:
42.86
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
Y473
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Chimpanzee
Pan troglodytes
XP_519057
852
98261
Y471
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
Y498
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Dog
Lupus familis
XP_533084
854
98472
Y473
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
Y472
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Rat
Rattus norvegicus
NP_001100825
745
86357
E409
N
H
L
V
E
R
G
E
Y
D
M
A
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
Y904
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Chicken
Gallus gallus
NP_001012877
804
93396
V447
N
T
I
I
V
Q
A
V
V
D
H
L
K
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
Y473
H
D
F
L
K
T
D
Y
E
G
F
A
T
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
D473
L
Y
E
F
L
K
F
D
V
C
G
F
L
N
L
Honey Bee
Apis mellifera
XP_624100
842
97559
P475
Y
E
Y
L
K
M
D
P
D
G
F
L
Q
L
V
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
V513
I
A
C
L
F
N
N
V
K
Q
F
R
K
L
V
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
L451
M
D
P
R
N
A
V
L
M
Q
T
L
G
E
L
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
H512
L
A
T
N
P
S
F
H
K
D
L
L
A
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
H515
L
A
T
N
P
S
Y
H
K
E
L
L
S
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
0
N.A.
80
N.A.
0
40
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
13.3
N.A.
100
N.A.
6.6
73.3
46.6
20
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
7
7
0
0
0
0
54
14
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
14
0
0
0
0
54
7
7
20
0
0
0
0
7
% D
% Glu:
0
47
7
0
47
0
0
7
47
7
0
0
0
7
0
% E
% Phe:
0
0
47
7
7
0
14
0
0
0
60
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
54
7
0
7
0
0
% G
% His:
47
7
0
0
0
0
0
14
0
0
7
0
0
0
0
% H
% Ile:
7
0
7
7
0
0
0
0
0
0
0
0
0
0
47
% I
% Lys:
0
0
0
0
14
7
0
0
20
0
0
0
14
7
7
% K
% Leu:
20
0
7
60
7
0
0
7
0
0
14
34
7
60
14
% L
% Met:
7
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% M
% Asn:
14
0
0
14
7
7
7
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
7
0
14
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
14
0
0
7
0
0
% Q
% Arg:
0
0
0
7
0
7
0
0
0
0
0
7
0
7
0
% R
% Ser:
0
0
0
0
0
54
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
7
14
0
0
7
0
0
0
0
7
0
47
7
0
% T
% Val:
0
0
0
7
7
0
7
14
14
0
0
0
0
0
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
0
0
0
7
47
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _