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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
41.52
Human Site:
Y620
Identified Species:
65.24
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
Y620
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Chimpanzee
Pan troglodytes
XP_519057
852
98261
Y618
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
Y645
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Dog
Lupus familis
XP_533084
854
98472
Y620
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
Y619
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Rat
Rattus norvegicus
NP_001100825
745
86357
I551
K
H
N
L
F
S
S
I
K
D
K
I
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
Y1051
H
E
K
Q
I
S
L
Y
A
E
F
D
R
P
N
Chicken
Gallus gallus
NP_001012877
804
93396
E591
D
S
T
H
C
P
L
E
K
A
L
E
I
C
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
Y620
H
E
R
Q
I
S
L
Y
A
E
F
D
R
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
Y617
Q
K
K
L
I
S
L
Y
A
I
F
D
R
N
K
Honey Bee
Apis mellifera
XP_624100
842
97559
Y620
H
G
L
L
V
Q
L
Y
A
N
Y
S
R
D
K
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
Y668
A
D
K
A
V
Q
L
Y
A
E
Y
D
Q
K
K
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
F593
E
Q
C
E
Q
R
N
F
I
K
E
M
V
F
L
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
Y665
H
D
M
Q
V
E
L
Y
A
D
Y
D
L
K
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
Y677
H
D
M
Q
V
E
L
Y
A
E
Y
D
T
K
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
6.6
N.A.
86.6
N.A.
53.3
40
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
N.A.
100
N.A.
66.6
46.6
66.6
26.6
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
80
7
0
0
0
0
0
% A
% Cys:
0
0
7
0
7
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
20
0
0
0
0
0
0
0
14
0
74
0
7
0
% D
% Glu:
7
47
0
7
0
14
0
7
0
60
7
7
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
7
0
0
20
0
0
7
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
67
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
54
0
0
7
7
7
0
7
7
0
0
% I
% Lys:
7
7
54
0
0
0
0
0
14
7
7
0
0
20
20
% K
% Leu:
0
0
7
20
0
0
87
0
0
0
7
0
7
7
14
% L
% Met:
0
0
14
0
0
0
0
0
0
0
0
7
0
0
14
% M
% Asn:
0
0
7
0
0
0
7
0
0
7
0
0
0
7
47
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
47
0
% P
% Gln:
7
7
0
60
7
14
0
0
0
0
0
0
7
0
7
% Q
% Arg:
0
0
7
0
0
7
0
0
0
0
0
0
60
0
0
% R
% Ser:
0
7
0
0
0
60
7
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
27
0
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
60
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _