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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED10
All Species:
39.39
Human Site:
S79
Identified Species:
57.78
UniProt:
P49755
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49755
NP_006818.3
219
24976
S79
S
H
L
K
I
T
D
S
A
G
H
I
L
Y
S
Chimpanzee
Pan troglodytes
XP_510074
371
40763
S231
S
H
L
K
I
T
D
S
A
G
H
I
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001089815
336
37115
S196
S
H
L
K
I
T
D
S
A
G
H
I
L
Y
S
Dog
Lupus familis
XP_854043
219
24762
S79
T
H
L
K
I
T
D
S
A
G
H
I
L
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1D4
219
24892
S79
T
H
L
K
I
T
D
S
A
G
H
I
L
Y
A
Rat
Rattus norvegicus
Q63584
219
24839
S79
T
H
L
K
I
T
D
S
A
G
H
I
L
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506639
244
27530
S104
T
H
L
R
I
T
D
S
A
G
H
I
L
Y
S
Chicken
Gallus gallus
NP_001006482
219
24785
S76
A
N
L
K
I
T
D
S
A
G
H
I
L
Y
A
Frog
Xenopus laevis
NP_001090170
207
23927
H67
K
I
T
D
S
A
G
H
I
L
Y
S
K
E
D
Zebra Danio
Brachydanio rerio
NP_999863
209
24423
S66
T
N
L
K
I
T
D
S
S
G
H
I
L
Y
V
Tiger Blowfish
Takifugu rubipres
Q90515
213
24635
S73
S
I
F
K
I
T
D
S
S
S
H
T
L
Y
S
Fruit Fly
Dros. melanogaster
Q8SXY6
206
23673
I68
A
R
D
T
K
G
H
I
L
S
Q
K
E
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505879
204
23662
G76
E
N
F
A
D
L
K
G
K
F
A
F
T
A
D
Sea Urchin
Strong. purpuratus
XP_791690
154
18084
D33
G
K
F
A
F
T
T
D
D
Y
D
T
Y
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P54837
211
24088
V70
N
L
F
V
R
D
S
V
G
N
E
Y
R
R
K
Red Bread Mold
Neurospora crassa
Q9HEK4
215
24521
H73
N
M
H
I
S
D
S
H
G
N
E
Y
G
K
A
Conservation
Percent
Protein Identity:
100
58.7
64.2
94.9
N.A.
92.6
93.1
N.A.
67.2
80.8
78.5
79.4
78.5
53.4
N.A.
53.8
52
Protein Similarity:
100
58.7
64.5
96.3
N.A.
94.9
95.4
N.A.
74.5
84.4
84
86.3
84.4
66.2
N.A.
71.2
62.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
80
0
73.3
66.6
0
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
93.3
73.3
13.3
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.5
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
57.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
0
7
0
0
50
0
7
0
0
7
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
7
13
63
7
7
0
7
0
0
0
13
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
13
0
7
13
0
% E
% Phe:
0
0
25
0
7
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
7
0
0
0
0
7
7
7
13
57
0
0
7
0
0
% G
% His:
0
44
7
0
0
0
7
13
0
0
63
0
0
7
0
% H
% Ile:
0
13
0
7
63
0
0
7
7
0
0
57
0
0
13
% I
% Lys:
7
7
0
57
7
0
7
0
7
0
0
7
7
7
7
% K
% Leu:
0
7
57
0
0
7
0
0
7
7
0
0
63
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
19
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
7
0
7
7
0
0
0
0
0
0
0
7
7
0
% R
% Ser:
25
0
0
0
13
0
13
63
13
13
0
7
0
0
38
% S
% Thr:
32
0
7
7
0
69
7
0
0
0
0
13
7
0
0
% T
% Val:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
7
13
7
63
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _