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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED10
All Species:
33.33
Human Site:
T114
Identified Species:
48.89
UniProt:
P49755
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49755
NP_006818.3
219
24976
T114
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Chimpanzee
Pan troglodytes
XP_510074
371
40763
T266
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Rhesus Macaque
Macaca mulatta
XP_001089815
336
37115
T231
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Dog
Lupus familis
XP_854043
219
24762
T114
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1D4
219
24892
T114
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Rat
Rattus norvegicus
Q63584
219
24839
T114
V
C
F
E
S
K
G
T
G
R
I
P
D
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506639
244
27530
T139
A
C
F
E
S
K
G
T
G
R
T
P
D
Q
L
Chicken
Gallus gallus
NP_001006482
219
24785
P111
A
C
F
E
S
K
L
P
V
G
T
G
R
M
P
Frog
Xenopus laevis
NP_001090170
207
23927
A102
D
S
K
L
P
A
G
A
G
R
V
P
D
Q
L
Zebra Danio
Brachydanio rerio
NP_999863
209
24423
P101
V
C
F
E
S
K
S
P
M
G
T
G
R
V
P
Tiger Blowfish
Takifugu rubipres
Q90515
213
24635
T108
V
C
F
E
S
K
C
T
G
R
V
P
D
Q
L
Fruit Fly
Dros. melanogaster
Q8SXY6
206
23673
R103
S
K
V
P
A
H
Q
R
G
V
I
Q
E
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505879
204
23662
L111
K
R
E
V
S
L
I
L
K
H
G
V
E
A
K
Sea Urchin
Strong. purpuratus
XP_791690
154
18084
K68
V
K
H
G
V
E
A
K
S
Y
E
D
L
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P54837
211
24088
Q105
V
C
F
E
N
Q
A
Q
Y
R
G
R
S
L
S
Red Bread Mold
Neurospora crassa
Q9HEK4
215
24521
T108
V
C
F
E
N
Y
L
T
A
K
Y
V
E
N
P
Conservation
Percent
Protein Identity:
100
58.7
64.2
94.9
N.A.
92.6
93.1
N.A.
67.2
80.8
78.5
79.4
78.5
53.4
N.A.
53.8
52
Protein Similarity:
100
58.7
64.5
96.3
N.A.
94.9
95.4
N.A.
74.5
84.4
84
86.3
84.4
66.2
N.A.
71.2
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
33.3
46.6
40
86.6
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
33.3
53.3
40
93.3
26.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.5
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
57.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
7
7
13
7
7
0
0
0
0
13
0
% A
% Cys:
0
75
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
7
57
0
0
% D
% Glu:
0
0
7
75
0
7
0
0
0
0
7
0
19
0
0
% E
% Phe:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
50
0
63
13
13
13
0
0
0
% G
% His:
0
0
7
0
0
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
44
0
0
0
0
% I
% Lys:
7
13
7
0
0
63
0
7
7
7
0
0
0
0
13
% K
% Leu:
0
0
0
7
0
7
13
7
0
0
0
0
7
7
57
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
7
7
0
0
13
0
0
0
57
0
0
19
% P
% Gln:
0
0
0
0
0
7
7
7
0
0
0
7
0
57
0
% Q
% Arg:
0
7
0
0
0
0
0
7
0
63
0
7
13
0
0
% R
% Ser:
7
7
0
0
69
0
7
0
7
0
0
0
7
0
13
% S
% Thr:
0
0
0
0
0
0
0
57
0
0
19
0
0
0
0
% T
% Val:
69
0
7
7
7
0
0
0
7
7
13
13
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
7
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _