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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED10
All Species:
51.82
Human Site:
Y167
Identified Species:
76
UniProt:
P49755
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49755
NP_006818.3
219
24976
Y167
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Chimpanzee
Pan troglodytes
XP_510074
371
40763
Y319
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001089815
336
37115
Y284
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Dog
Lupus familis
XP_854043
219
24762
Y167
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1D4
219
24892
Y167
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Rat
Rattus norvegicus
Q63584
219
24839
Y167
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506639
244
27530
Y192
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Chicken
Gallus gallus
NP_001006482
219
24785
Y167
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Frog
Xenopus laevis
NP_001090170
207
23927
Y155
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Zebra Danio
Brachydanio rerio
NP_999863
209
24423
Y157
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Tiger Blowfish
Takifugu rubipres
Q90515
213
24635
Y161
S
I
V
N
D
F
A
Y
M
K
K
R
E
E
E
Fruit Fly
Dros. melanogaster
Q8SXY6
206
23673
L154
S
I
V
R
D
F
V
L
M
R
K
R
E
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505879
204
23662
F152
S
I
T
K
D
F
A
F
M
R
Q
R
E
E
E
Sea Urchin
Strong. purpuratus
XP_791690
154
18084
E107
F
G
Y
M
K
K
R
E
E
E
M
R
D
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P54837
211
24088
Y160
E
I
V
D
E
L
T
Y
L
K
N
R
E
E
R
Red Bread Mold
Neurospora crassa
Q9HEK4
215
24521
Y164
E
V
V
N
E
M
D
Y
L
R
A
R
E
Q
K
Conservation
Percent
Protein Identity:
100
58.7
64.2
94.9
N.A.
92.6
93.1
N.A.
67.2
80.8
78.5
79.4
78.5
53.4
N.A.
53.8
52
Protein Similarity:
100
58.7
64.5
96.3
N.A.
94.9
95.4
N.A.
74.5
84.4
84
86.3
84.4
66.2
N.A.
71.2
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
100
73.3
N.A.
66.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
100
80
N.A.
86.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.5
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
57.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
75
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
82
0
7
0
0
0
0
0
7
0
0
% D
% Glu:
13
0
0
0
13
0
0
7
7
7
0
0
94
88
82
% E
% Phe:
7
0
0
0
0
82
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
88
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
7
7
0
0
0
75
75
0
0
0
7
% K
% Leu:
0
0
0
0
0
7
0
7
13
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
7
0
0
82
0
7
0
0
0
0
% M
% Asn:
0
0
0
75
0
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
0
7
0
0
7
0
0
19
0
100
0
0
7
% R
% Ser:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
7
0
0
0
0
0
0
7
0
% T
% Val:
0
7
88
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _