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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS6
All Species:
37.27
Human Site:
S411
Identified Species:
63.08
UniProt:
P49758
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49758
NP_004287.3
472
54423
S411
S
H
S
Y
E
I
T
S
Q
N
V
K
D
G
G
Chimpanzee
Pan troglodytes
XP_001147276
490
56494
S411
S
H
S
Y
E
I
T
S
Q
N
V
K
D
G
G
Rhesus Macaque
Macaca mulatta
XP_001084681
472
54477
S411
S
H
S
Y
E
I
T
S
Q
N
V
K
D
G
G
Dog
Lupus familis
XP_537503
683
78241
S398
S
H
S
Y
E
I
T
S
Q
N
V
K
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2H2
472
54513
S411
S
H
S
Y
E
I
T
S
Q
N
V
K
D
G
G
Rat
Rattus norvegicus
P49803
477
55673
T408
S
K
S
Y
D
K
T
T
Q
N
V
K
E
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514330
608
70692
T408
S
K
S
Y
D
K
T
T
Q
N
V
K
E
P
G
Chicken
Gallus gallus
XP_421174
472
54583
S411
S
H
S
Y
E
K
T
S
Q
N
V
K
D
P
G
Frog
Xenopus laevis
NP_001079945
471
54554
S410
S
H
S
F
E
K
T
S
Q
N
V
K
D
P
G
Zebra Danio
Brachydanio rerio
NP_001030340
489
56551
S410
S
H
S
Y
E
R
T
S
Q
N
L
K
D
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523380
647
70137
A571
Q
E
F
L
A
P
E
A
P
C
P
V
N
V
D
Honey Bee
Apis mellifera
XP_393403
510
59946
V443
D
A
S
C
P
I
N
V
D
S
Q
S
Y
E
I
Nematode Worm
Caenorhab. elegans
P49809
555
63260
V488
A
A
T
S
P
V
N
V
D
C
K
V
M
E
V
Sea Urchin
Strong. purpuratus
XP_782272
467
54702
R402
S
K
I
L
D
T
T
R
K
N
M
K
N
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
98.9
64.4
N.A.
97.6
71.4
N.A.
57.2
92.8
87.2
79.1
N.A.
40.3
50.7
45.5
59.7
Protein Similarity:
100
96.3
99.5
65.7
N.A.
99.3
85.3
N.A.
67.5
94.4
92.5
87.7
N.A.
53.1
68.4
60.5
73.7
P-Site Identity:
100
100
100
100
N.A.
100
60
N.A.
60
86.6
80
80
N.A.
0
13.3
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
80
86.6
86.6
86.6
N.A.
13.3
20
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
8
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
8
0
0
0
22
0
0
0
15
0
0
0
58
0
8
% D
% Glu:
0
8
0
0
58
0
8
0
0
0
0
0
15
15
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
36
72
% G
% His:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
43
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
22
0
0
0
29
0
0
8
0
8
79
0
0
0
% K
% Leu:
0
0
0
15
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
79
0
0
15
0
8
% N
% Pro:
0
0
0
0
15
8
0
0
8
0
8
0
0
43
0
% P
% Gln:
8
0
0
0
0
0
0
0
72
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
79
0
79
8
0
0
0
58
0
8
0
8
0
0
0
% S
% Thr:
0
0
8
0
0
8
79
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
15
0
0
65
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
65
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _