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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
15.15
Human Site:
S128
Identified Species:
27.78
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
S128
H
S
T
S
H
R
R
S
H
G
K
S
H
R
R
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
S128
H
S
T
S
H
R
R
S
H
G
K
S
H
R
R
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
S128
H
S
T
S
H
R
R
S
H
G
K
S
H
R
R
Dog
Lupus familis
XP_531875
481
57271
S128
C
S
S
H
Q
S
R
S
K
S
H
R
R
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
H128
H
T
S
Q
H
H
S
H
G
K
S
H
R
R
K
Rat
Rattus norvegicus
Q63117
490
58467
S128
A
S
S
R
S
Q
Q
S
S
K
R
S
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
V138
R
R
K
R
S
R
S
V
E
D
D
E
E
G
H
Chicken
Gallus gallus
Q5ZIU3
526
59419
D129
G
P
N
N
C
G
Y
D
D
D
Q
G
S
Y
I
Frog
Xenopus laevis
NP_001091432
462
54946
L129
E
D
D
E
E
G
H
L
I
C
E
S
G
D
V
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S154
R
T
R
S
Y
S
A
S
S
S
R
S
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
A446
Q
N
E
M
S
K
S
A
L
G
L
H
F
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
R118
Q
V
L
E
C
W
D
R
E
R
K
E
M
V
A
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
N168
C
G
T
A
A
T
S
N
S
T
Y
I
T
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
20
26.6
N.A.
6.6
0
6.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
40
53.3
N.A.
6.6
13.3
13.3
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
8
8
0
0
0
0
0
0
8
% A
% Cys:
16
0
0
0
16
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
8
8
8
16
8
0
8
8
0
% D
% Glu:
8
0
8
16
8
0
0
0
16
0
8
16
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
0
0
0
16
0
0
8
31
0
8
8
8
8
% G
% His:
31
0
0
8
31
8
8
8
24
0
8
16
24
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
8
% I
% Lys:
0
0
8
0
0
8
0
0
8
16
31
0
0
8
8
% K
% Leu:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
16
0
0
8
8
8
8
0
0
0
8
0
0
0
0
% Q
% Arg:
16
8
8
16
0
31
31
8
0
8
16
8
16
39
31
% R
% Ser:
0
39
24
31
24
16
31
47
24
16
8
47
16
8
8
% S
% Thr:
0
16
31
0
0
8
0
0
0
8
0
0
8
8
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _