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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
17.58
Human Site:
S153
Identified Species:
32.22
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
S153
E
G
H
L
I
C
Q
S
G
D
V
L
S
A
R
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
S153
E
G
H
L
I
C
Q
S
G
D
V
L
S
A
R
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
S153
E
G
H
L
I
C
Q
S
G
D
V
L
S
A
R
Dog
Lupus familis
XP_531875
481
57271
D153
H
L
I
C
Q
S
G
D
V
L
R
A
R
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
G153
G
H
L
I
C
Q
S
G
D
V
L
S
A
R
Y
Rat
Rattus norvegicus
Q63117
490
58467
Q153
C
R
I
G
D
W
L
Q
E
R
Y
E
I
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
T163
A
R
Y
E
I
V
A
T
L
G
E
G
A
F
G
Chicken
Gallus gallus
Q5ZIU3
526
59419
G154
Y
E
V
L
K
V
I
G
K
G
S
F
G
Q
V
Frog
Xenopus laevis
NP_001091432
462
54946
K154
V
G
E
G
A
F
G
K
V
V
E
C
I
D
L
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S179
E
G
H
L
I
C
R
S
G
D
V
L
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
T471
D
G
H
L
I
Y
H
T
G
D
I
L
H
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
I143
R
E
A
A
M
I
E
I
E
M
L
Q
Q
L
G
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
K193
L
P
Q
L
P
L
S
K
L
S
Y
Q
S
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
6.6
6.6
6.6
80
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
20
0
N.A.
26.6
6.6
6.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
8
0
0
0
0
8
16
24
0
% A
% Cys:
8
0
0
8
8
31
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
8
39
0
0
0
8
0
% D
% Glu:
31
16
8
8
0
0
8
0
16
0
16
8
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% F
% Gly:
8
47
0
16
0
0
16
16
39
16
0
8
8
0
24
% G
% His:
8
8
39
0
0
0
8
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
16
8
47
8
8
8
0
0
8
0
16
0
0
% I
% Lys:
0
0
0
0
8
0
0
16
8
0
0
0
0
0
0
% K
% Leu:
8
8
8
54
0
8
8
0
16
8
16
39
0
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
8
24
8
0
0
0
16
16
8
0
% Q
% Arg:
8
16
0
0
0
0
8
0
0
8
8
0
8
8
39
% R
% Ser:
0
0
0
0
0
8
16
31
0
8
8
8
31
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
16
0
0
16
16
31
0
0
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
0
0
0
0
16
0
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _