KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
18.48
Human Site:
S24
Identified Species:
33.89
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
S24
W
D
Y
G
K
W
R
S
S
S
S
H
K
R
R
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
S24
W
D
Y
G
K
W
R
S
S
S
S
H
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
S24
W
D
Y
G
K
W
R
S
S
S
S
H
K
R
R
Dog
Lupus familis
XP_531875
481
57271
S24
S
W
G
H
E
S
Y
S
G
S
H
K
R
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
S24
W
D
Y
G
T
W
R
S
S
S
S
H
K
R
K
Rat
Rattus norvegicus
Q63117
490
58467
R24
S
Y
R
W
K
R
R
R
S
Y
S
R
E
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
S34
K
R
K
R
R
S
P
S
S
A
R
D
N
K
R
Chicken
Gallus gallus
Q5ZIU3
526
59419
K25
L
F
E
D
N
S
N
K
R
T
V
L
T
T
Q
Frog
Xenopus laevis
NP_001091432
462
54946
R25
S
K
C
Y
K
R
K
R
S
Q
S
S
E
E
E
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
E50
Y
S
S
S
S
E
R
E
R
R
A
R
G
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y342
Q
T
F
D
P
Y
A
Y
P
K
P
N
Q
M
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
M14
H
E
F
P
H
T
H
M
D
R
R
P
R
K
R
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
R64
S
F
L
T
D
N
L
R
N
S
L
D
L
N
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
86.6
26.6
N.A.
20
0
20
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
93.3
33.3
N.A.
40
13.3
33.3
26.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
0
16
8
0
0
0
8
0
0
16
0
0
0
% D
% Glu:
0
8
8
0
8
8
0
8
0
0
0
0
16
8
16
% E
% Phe:
0
16
16
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
31
0
0
0
0
8
0
0
0
8
0
0
% G
% His:
8
0
0
8
8
0
8
0
0
0
8
31
0
16
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
0
39
0
8
8
0
8
0
8
31
24
8
% K
% Leu:
8
0
8
0
0
0
8
0
0
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
8
8
0
8
0
0
8
8
8
0
% N
% Pro:
0
0
0
8
8
0
8
0
8
0
8
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
24
% Q
% Arg:
0
8
8
8
8
16
47
24
16
16
16
16
16
31
54
% R
% Ser:
31
8
8
8
8
24
0
47
54
47
47
8
0
0
0
% S
% Thr:
0
8
0
8
8
8
0
0
0
8
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
31
8
0
8
0
31
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
31
8
0
8
8
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _