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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
30.61
Human Site:
Y301
Identified Species:
56.11
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
Y301
I
L
F
V
Q
S
D
Y
T
E
A
Y
N
P
K
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
Y301
I
L
F
V
Q
S
D
Y
T
E
A
Y
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
Y301
I
L
F
V
Q
S
D
Y
T
E
A
Y
N
P
K
Dog
Lupus familis
XP_531875
481
57271
Y299
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
Y300
I
L
F
V
K
S
D
Y
T
E
A
Y
N
P
K
Rat
Rattus norvegicus
Q63117
490
58467
F296
I
L
F
V
N
S
E
F
E
T
L
Y
N
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
Y298
I
L
F
V
Q
S
D
Y
V
E
E
Y
N
P
K
Chicken
Gallus gallus
Q5ZIU3
526
59419
I269
D
A
L
H
K
N
R
I
I
H
C
D
L
K
P
Frog
Xenopus laevis
NP_001091432
462
54946
Y281
I
L
F
V
H
S
D
Y
V
V
N
F
N
P
T
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y327
I
L
F
V
N
S
D
Y
T
V
T
Y
N
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y618
I
L
F
V
D
S
D
Y
T
S
H
Y
N
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
V256
R
D
V
C
Y
K
R
V
P
K
S
S
A
I
K
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
L466
P
L
K
T
V
Q
S
L
S
K
R
R
R
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
93.3
46.6
N.A.
86.6
0
60
66.6
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
100
60
N.A.
86.6
13.3
66.6
73.3
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
31
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
70
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
39
8
0
0
16
8
% E
% Phe:
0
0
77
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
8
8
0
0
8
8
% H
% Ile:
77
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
24
8
0
0
0
16
8
0
0
8
62
% K
% Leu:
0
85
8
0
0
0
0
8
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
8
0
0
0
0
8
0
77
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
47
8
% P
% Gln:
0
0
0
0
31
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
16
0
0
0
8
8
8
0
0
% R
% Ser:
0
0
0
0
0
77
8
0
8
8
8
8
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
0
47
8
8
0
0
0
8
% T
% Val:
0
0
8
77
8
0
0
8
24
24
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
0
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _