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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
16.67
Human Site:
Y80
Identified Species:
30.56
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
Y80
I
D
E
Y
R
N
D
Y
T
Q
G
C
E
P
G
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
Y80
I
D
E
Y
R
N
D
Y
T
Q
G
C
E
P
G
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
Y80
I
D
E
Y
R
N
D
Y
N
Q
E
C
E
P
G
Dog
Lupus familis
XP_531875
481
57271
Y80
V
D
E
Y
R
N
D
Y
C
E
G
Y
V
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
Y80
V
D
E
Y
R
N
D
Y
M
G
Y
E
P
G
H
Rat
Rattus norvegicus
Q63117
490
58467
G80
E
E
R
S
P
S
F
G
E
D
C
Y
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
D90
E
F
G
H
H
H
R
D
H
E
S
G
Y
H
N
Chicken
Gallus gallus
Q5ZIU3
526
59419
P81
V
K
A
S
V
M
T
P
E
Q
A
M
K
Q
Y
Frog
Xenopus laevis
NP_001091432
462
54946
Y81
D
Q
K
H
H
N
R
Y
S
K
S
S
G
Q
S
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
P106
Q
N
R
D
H
R
T
P
S
N
Y
Y
S
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
S398
Y
A
S
P
A
S
S
S
S
N
K
Q
P
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
A70
S
L
C
V
K
G
V
A
R
N
G
S
P
P
W
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
D120
N
S
S
R
V
D
E
D
A
D
D
D
I
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
46.6
0
N.A.
0
6.6
13.3
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
73.3
N.A.
53.3
13.3
N.A.
20
20
40
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
8
24
0
0
0
% C
% Asp:
8
39
0
8
0
8
39
16
0
16
8
8
0
0
8
% D
% Glu:
16
8
39
0
0
0
8
0
16
16
8
8
24
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
8
0
8
0
8
31
8
16
8
24
% G
% His:
0
0
0
16
24
8
0
0
8
0
0
0
0
8
8
% H
% Ile:
24
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
8
8
0
8
0
0
0
0
8
8
0
8
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
8
0
0
0
47
0
0
8
24
0
0
0
0
8
% N
% Pro:
0
0
0
8
8
0
0
16
0
0
0
0
24
39
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
31
0
8
0
24
8
% Q
% Arg:
0
0
16
8
39
8
16
0
8
0
0
0
0
8
8
% R
% Ser:
8
8
16
16
0
16
8
8
24
0
16
16
8
8
16
% S
% Thr:
0
0
0
0
0
0
16
0
16
0
0
0
0
0
0
% T
% Val:
24
0
0
8
16
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
39
0
0
0
47
0
0
16
24
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _