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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK1
All Species:
15.15
Human Site:
Y97
Identified Species:
27.78
UniProt:
P49759
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49759
NP_004062.2
484
57291
Y97
Q
R
D
H
E
S
R
Y
Q
N
H
S
S
K
S
Chimpanzee
Pan troglodytes
XP_001170873
484
57300
Y97
Q
R
D
H
E
S
R
Y
Q
N
H
S
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001093219
484
57330
Y97
H
R
D
H
E
S
R
Y
Q
N
H
S
S
K
S
Dog
Lupus familis
XP_531875
481
57271
Y97
H
R
D
V
D
S
G
Y
R
V
H
C
S
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P22518
483
57077
Q97
G
E
P
G
S
R
Y
Q
M
H
S
S
K
S
S
Rat
Rattus norvegicus
Q63117
490
58467
E97
R
H
R
R
R
S
R
E
R
G
P
Y
R
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513861
482
56823
G107
S
K
S
S
G
R
S
G
R
S
S
Y
K
K
K
Chicken
Gallus gallus
Q5ZIU3
526
59419
N98
K
L
T
T
F
E
H
N
E
I
F
G
Y
T
E
Frog
Xenopus laevis
NP_001091432
462
54946
H98
S
S
S
H
K
K
R
H
R
K
H
H
H
S
R
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
G123
P
S
Y
D
F
R
R
G
R
D
R
D
R
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
S415
Q
Q
Q
Q
Q
Q
Q
S
Q
L
Q
Q
S
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
I87
D
D
K
D
G
H
Y
I
F
E
L
G
D
D
L
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
S137
E
Q
P
I
Q
F
S
S
P
L
I
L
P
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
78.7
N.A.
89
50
N.A.
86.5
22.4
67.9
53.7
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
86.7
N.A.
93.5
65.9
N.A.
91.7
39.1
79.1
68.2
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
53.3
N.A.
13.3
13.3
N.A.
6.6
0
20
6.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
20
26.6
N.A.
26.6
13.3
40
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
31
16
8
0
0
0
0
8
0
8
8
8
8
% D
% Glu:
8
8
0
0
24
8
0
8
8
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
16
8
0
0
8
0
8
0
0
0
0
% F
% Gly:
8
0
0
8
16
0
8
16
0
8
0
16
0
0
0
% G
% His:
16
8
0
31
0
8
8
8
0
8
39
8
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
8
8
0
0
0
0
% I
% Lys:
8
8
8
0
8
8
0
0
0
8
0
0
16
39
8
% K
% Leu:
0
8
0
0
0
0
0
0
0
16
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
24
0
0
0
8
0
% N
% Pro:
8
0
16
0
0
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
24
16
8
8
16
8
8
8
31
0
8
8
0
0
0
% Q
% Arg:
8
31
8
8
8
24
47
0
39
0
8
0
16
0
16
% R
% Ser:
16
16
16
8
8
39
16
16
0
8
16
31
39
24
54
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
0
16
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
16
31
0
0
0
16
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _