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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK2
All Species:
11.52
Human Site:
S110
Identified Species:
23.03
UniProt:
P49760
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49760
NP_003984.2
499
60090
S110
R
E
N
S
S
Y
R
S
Q
R
S
S
R
R
K
Chimpanzee
Pan troglodytes
XP_513855
498
59985
Q110
E
N
S
S
Y
R
S
Q
R
S
S
R
R
K
H
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
T251
R
E
R
G
P
Y
R
T
R
K
H
A
H
H
C
Dog
Lupus familis
XP_547549
536
63798
S146
R
E
N
S
S
Y
R
S
Q
R
S
S
R
R
K
Cat
Felis silvestris
Mouse
Mus musculus
O35491
499
59936
S110
R
E
N
S
S
Y
R
S
Q
R
S
S
R
R
K
Rat
Rattus norvegicus
Q63117
490
58467
C110
T
R
K
H
A
H
H
C
H
K
R
R
T
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIU3
526
59419
G110
Y
T
E
I
Y
F
L
G
P
N
A
K
K
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
R134
D
R
E
D
S
Y
R
R
K
G
S
R
R
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
N426
Q
S
N
S
V
I
F
N
H
S
G
Q
Q
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTF3
817
89866
P408
T
F
G
A
K
L
V
P
F
E
K
N
E
I
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
L94
I
F
E
L
G
D
D
L
T
P
R
Y
K
I
Y
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
P260
P
A
Q
I
A
S
L
P
Q
S
N
L
K
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
51.2
91.5
N.A.
96.7
59.9
N.A.
N.A.
21.2
N.A.
74.9
N.A.
37
N.A.
20.4
N.A.
Protein Similarity:
100
99.8
62.3
91.7
N.A.
98.1
73.7
N.A.
N.A.
39.7
N.A.
83.8
N.A.
48.4
N.A.
34.5
N.A.
P-Site Identity:
100
20
26.6
100
N.A.
100
6.6
N.A.
N.A.
6.6
N.A.
33.3
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
40
53.3
100
N.A.
100
26.6
N.A.
N.A.
33.3
N.A.
46.6
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
17
0
0
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
34
25
0
0
0
0
0
0
9
0
0
9
0
0
% E
% Phe:
0
17
0
0
0
9
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
9
0
0
9
0
9
9
0
0
0
0
% G
% His:
0
0
0
9
0
9
9
0
17
0
9
0
9
17
17
% H
% Ile:
9
0
0
17
0
9
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
9
0
9
0
0
0
9
17
9
9
25
25
25
% K
% Leu:
0
0
0
9
0
9
17
9
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
34
0
0
0
0
9
0
9
9
9
0
0
0
% N
% Pro:
9
0
0
0
9
0
0
17
9
9
0
0
0
0
0
% P
% Gln:
9
0
9
0
0
0
0
9
34
0
0
9
9
0
25
% Q
% Arg:
34
17
9
0
0
9
42
9
17
25
17
25
42
42
0
% R
% Ser:
0
9
9
42
34
9
9
25
0
25
42
25
0
0
9
% S
% Thr:
17
9
0
0
0
0
0
9
9
0
0
0
9
0
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
17
42
0
0
0
0
0
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _