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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLK2 All Species: 30.91
Human Site: S402 Identified Species: 61.82
UniProt: P49760 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49760 NP_003984.2 499 60090 S402 R I L G P I P S R M I R K T R
Chimpanzee Pan troglodytes XP_513855 498 59985 S401 R I L G P I P S R M I R K T R
Rhesus Macaque Macaca mulatta XP_001100690 638 73454 S543 K I L G P I P S H M I H R T R
Dog Lupus familis XP_547549 536 63798 S438 R I L G P I P S R M I R K T R
Cat Felis silvestris
Mouse Mus musculus O35491 499 59936 S401 R I L G P V P S R M I R K T R
Rat Rattus norvegicus Q63117 490 58467 S395 K I L G P I P S H M I H R T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIU3 526 59419 S383 R A K N F V S S K G Y P R Y C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038344 526 62655 S426 R I L G P V P S R M I R K T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49762 832 95705 N722 I P Y R M A R N H T L Y S K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XTF3 817 89866 S697 R A R T F I T S K G Y P R Y C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51567 427 49548 P340 E R V L G P F P Q Q M L K K V
Baker's Yeast Sacchar. cerevisiae P32350 737 83824 T566 I N G T P F P T D I I D K M F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 51.2 91.5 N.A. 96.7 59.9 N.A. N.A. 21.2 N.A. 74.9 N.A. 37 N.A. 20.4 N.A.
Protein Similarity: 100 99.8 62.3 91.7 N.A. 98.1 73.7 N.A. N.A. 39.7 N.A. 83.8 N.A. 48.4 N.A. 34.5 N.A.
P-Site Identity: 100 100 73.3 100 N.A. 93.3 73.3 N.A. N.A. 13.3 N.A. 93.3 N.A. 0 N.A. 20 N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 100 86.6 N.A. N.A. 33.3 N.A. 100 N.A. 13.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 56.9 43.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 17 9 9 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 9 59 9 0 0 0 0 17 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 25 0 0 17 0 0 0 % H
% Ile: 17 59 0 0 0 50 0 0 0 9 67 0 0 0 0 % I
% Lys: 17 0 9 0 0 0 0 0 17 0 0 0 59 17 0 % K
% Leu: 0 0 59 9 0 0 0 0 0 0 9 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 59 9 0 0 9 0 % M
% Asn: 0 9 0 9 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 0 67 9 67 9 0 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % Q
% Arg: 59 9 9 9 0 0 9 0 42 0 0 42 34 0 59 % R
% Ser: 0 0 0 0 0 0 9 75 0 0 0 0 9 0 0 % S
% Thr: 0 0 0 17 0 0 9 9 0 9 0 0 0 59 9 % T
% Val: 0 0 9 0 0 25 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 17 9 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _