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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLK2 All Species: 38.18
Human Site: T340 Identified Species: 76.36
UniProt: P49760 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49760 NP_003984.2 499 60090 T340 F D H E H H S T I V S T R H Y
Chimpanzee Pan troglodytes XP_513855 498 59985 T339 F D H E H H S T I V S T R H Y
Rhesus Macaque Macaca mulatta XP_001100690 638 73454 T481 F D H E H H T T I V A T R H Y
Dog Lupus familis XP_547549 536 63798 T376 F D H E H H S T I V S T R H Y
Cat Felis silvestris
Mouse Mus musculus O35491 499 59936 T339 F D H E H H S T I V S T R H Y
Rat Rattus norvegicus Q63117 490 58467 T333 F D H E H H T T I V A T R H Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIU3 526 59419 T306 Y E H Q R V Y T Y I Q S R F Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038344 526 62655 T364 F D H E H H S T I V S T R H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49762 832 95705 T655 F D H E H H S T I V S T R H Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XTF3 817 89866 T620 F D D Q R I Y T Y I Q S R F Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51567 427 49548 S282 Q D Q T Y I V S T R H Y R A P
Baker's Yeast Sacchar. cerevisiae P32350 737 83824 P503 F H Y E Y H P P V I S T R H Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 51.2 91.5 N.A. 96.7 59.9 N.A. N.A. 21.2 N.A. 74.9 N.A. 37 N.A. 20.4 N.A.
Protein Similarity: 100 99.8 62.3 91.7 N.A. 98.1 73.7 N.A. N.A. 39.7 N.A. 83.8 N.A. 48.4 N.A. 34.5 N.A.
P-Site Identity: 100 100 86.6 100 N.A. 100 86.6 N.A. N.A. 26.6 N.A. 100 N.A. 100 N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 60 N.A. 100 N.A. 100 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 56.9 43.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 17 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 84 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 75 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 84 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 75 0 67 75 0 0 0 0 9 0 0 75 0 % H
% Ile: 0 0 0 0 0 17 0 0 67 25 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 9 % P
% Gln: 9 0 9 17 0 0 0 0 0 0 17 0 0 0 0 % Q
% Arg: 0 0 0 0 17 0 0 0 0 9 0 0 100 0 0 % R
% Ser: 0 0 0 0 0 0 50 9 0 0 59 17 0 0 0 % S
% Thr: 0 0 0 9 0 0 17 84 9 0 0 75 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 9 67 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 0 17 0 17 0 17 0 0 9 0 0 92 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _