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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
9.09
Human Site:
S581
Identified Species:
16.67
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
S581
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
L
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
H442
M
L
Q
D
S
L
E
H
V
Q
L
F
D
L
M
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
S581
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
L
Dog
Lupus familis
XP_535541
381
44762
H333
M
L
Q
D
S
L
E
H
V
Q
L
F
D
L
M
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
S581
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
L
Rat
Rattus norvegicus
Q63117
490
58467
H442
M
L
Q
D
S
L
E
H
V
Q
L
F
D
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
L442
D
S
L
E
H
A
Q
L
F
D
L
I
R
R
M
Frog
Xenopus laevis
NP_001093358
497
58599
Q449
G
D
S
P
E
H
T
Q
L
F
D
L
L
S
R
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
D478
E
E
H
H
Q
L
F
D
L
I
E
A
M
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
L760
D
H
C
K
P
L
F
L
C
Q
L
S
D
S
E
Honey Bee
Apis mellifera
XP_395279
439
51412
H391
M
L
S
D
D
E
E
H
R
Q
L
F
D
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
P379
L
K
A
V
L
K
L
P
R
L
Q
N
L
I
M
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
W604
R
K
T
L
S
L
Q
W
P
E
K
N
K
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
20
100
20
N.A.
100
20
N.A.
N.A.
6.6
6.6
13.3
N.A.
46.6
13.3
N.A.
N.A.
P-Site Similarity:
100
33.3
100
33.3
N.A.
100
33.3
N.A.
N.A.
46.6
13.3
20
N.A.
60
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
31
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
16
8
0
31
8
0
0
8
0
8
8
0
62
0
0
% D
% Glu:
31
8
0
8
8
8
31
0
0
8
8
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
16
0
8
8
0
31
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
8
8
8
8
0
31
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
8
% I
% Lys:
0
16
0
31
0
8
24
0
0
0
8
0
8
0
0
% K
% Leu:
8
31
8
8
8
70
8
16
16
8
70
8
16
39
24
% L
% Met:
31
0
0
0
0
0
0
0
0
24
0
0
8
0
39
% M
% Asn:
0
24
0
0
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
0
8
31
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
24
0
8
0
16
8
0
39
8
24
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
16
0
0
0
8
16
8
% R
% Ser:
0
8
16
0
31
0
0
24
0
0
0
8
0
39
0
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
24
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _