KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
12.42
Human Site:
Y554
Identified Species:
22.78
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
Y554
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
D415
Y
K
G
G
L
V
W
D
E
N
S
S
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
Y554
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Dog
Lupus familis
XP_535541
381
44762
D306
Y
K
G
G
L
V
W
D
E
N
S
S
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
Y554
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Rat
Rattus norvegicus
Q63117
490
58467
D415
Y
K
G
G
L
V
W
D
E
N
S
S
D
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
T415
N
L
V
W
D
E
N
T
S
D
G
R
Y
V
Q
Frog
Xenopus laevis
NP_001093358
497
58599
N422
G
S
L
I
W
D
E
N
S
S
D
G
R
Y
V
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
A451
D
W
D
E
N
S
S
A
G
R
Y
V
R
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y733
Y
S
K
T
K
T
K
Y
F
Y
H
G
K
L
D
Honey Bee
Apis mellifera
XP_395279
439
51412
D364
Y
H
G
K
L
D
W
D
D
K
S
S
A
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
E352
K
K
V
D
R
H
S
E
K
Y
V
R
R
G
R
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
K577
D
K
M
F
Y
K
S
K
H
K
L
G
N
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
0
N.A.
N.A.
0
13.3
0
N.A.
46.6
0
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
N.A.
20
20
0
N.A.
53.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
8
8
16
0
31
8
8
8
0
24
0
8
% D
% Glu:
0
0
0
8
0
8
8
8
24
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
31
0
0
0
0
0
0
% F
% Gly:
8
0
31
24
0
0
0
0
8
0
8
47
24
39
0
% G
% His:
24
8
0
0
0
8
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
39
8
8
31
8
31
8
8
16
24
0
8
0
0
% K
% Leu:
0
8
8
0
31
0
0
0
0
0
8
0
0
31
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
8
0
24
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
24
0
24
8
0
0
0
0
8
0
16
24
0
39
% R
% Ser:
0
16
0
0
0
8
24
0
16
8
31
31
0
8
0
% S
% Thr:
0
0
24
8
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
24
0
0
0
0
8
8
0
8
31
% V
% Trp:
0
8
0
8
8
0
31
0
0
0
0
0
0
0
0
% W
% Tyr:
39
0
0
0
8
0
0
31
0
39
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _