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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VEGFB
All Species:
6.67
Human Site:
S181
Identified Species:
16.3
UniProt:
P49765
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49765
NP_003368.1
207
21602
S181
P
S
A
H
A
A
P
S
T
T
S
A
L
T
P
Chimpanzee
Pan troglodytes
XP_001144738
203
23119
L177
C
S
C
W
H
L
E
L
Y
K
Q
V
Q
H
S
Rhesus Macaque
Macaca mulatta
XP_001118308
188
21190
R163
T
C
R
C
H
C
R
R
R
S
F
L
R
C
Q
Dog
Lupus familis
XP_533245
188
21183
R163
T
C
R
C
R
C
Q
R
R
S
F
L
R
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
P49766
207
21896
S181
S
S
A
R
L
A
P
S
A
V
N
A
L
T
P
Rat
Rattus norvegicus
O35485
207
21851
S181
P
S
A
H
A
A
P
S
A
V
S
A
L
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508303
206
24087
K177
V
Q
D
L
Q
T
C
K
C
S
C
K
N
T
D
Chicken
Gallus gallus
P67964
216
25185
K187
V
Q
D
P
Q
T
C
K
C
S
C
K
F
T
D
Frog
Xenopus laevis
NP_001079058
148
17216
Q123
H
I
M
D
M
S
F
Q
Q
H
S
Q
C
E
C
Zebra Danio
Brachydanio rerio
O73682
188
21738
C163
P
L
T
C
K
C
S
C
K
F
T
Q
M
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
69.5
64.2
N.A.
86.9
86.9
N.A.
28.9
27.3
28
27.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.3
71.5
68.1
N.A.
90.3
90.3
N.A.
44.9
42.1
41.5
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
60
80
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
6.6
N.A.
66.6
80
N.A.
13.3
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
20
30
0
0
20
0
0
30
0
0
0
% A
% Cys:
10
20
10
30
0
30
20
10
20
0
20
0
10
20
20
% C
% Asp:
0
0
20
10
0
0
0
0
0
0
0
0
0
0
20
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
20
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
20
20
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
20
10
10
0
20
0
0
0
% K
% Leu:
0
10
0
10
10
10
0
10
0
0
0
20
30
0
0
% L
% Met:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
30
0
0
10
0
0
30
0
0
0
0
0
0
0
30
% P
% Gln:
0
20
0
0
20
0
10
10
10
0
10
20
10
10
20
% Q
% Arg:
0
0
20
10
10
0
10
20
20
0
0
0
20
0
0
% R
% Ser:
10
40
0
0
0
10
10
30
0
40
30
0
0
0
10
% S
% Thr:
20
0
10
0
0
20
0
0
10
10
10
0
0
40
0
% T
% Val:
20
0
0
0
0
0
0
0
0
20
0
10
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _