KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2B2
All Species:
36.06
Human Site:
T38
Identified Species:
61.03
UniProt:
P49770
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49770
NP_055054.1
351
38990
T38
S
E
E
M
A
R
E
T
L
G
L
L
R
Q
I
Chimpanzee
Pan troglodytes
XP_510071
351
38922
T38
S
E
E
M
A
R
E
T
L
G
L
L
R
Q
I
Rhesus Macaque
Macaca mulatta
XP_001096471
351
38950
T38
S
E
E
M
A
R
E
T
L
G
L
L
R
Q
I
Dog
Lupus familis
XP_547911
351
38990
T38
S
E
D
M
A
R
E
T
L
G
L
L
R
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99LD9
351
38879
T38
S
E
D
M
A
R
E
T
L
G
L
L
R
R
L
Rat
Rattus norvegicus
Q62818
351
38857
T38
S
E
D
M
A
R
E
T
L
G
L
L
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006481
351
39055
T38
S
E
D
T
A
R
Q
T
L
S
L
L
R
K
I
Frog
Xenopus laevis
NP_001080268
305
34202
A17
E
L
S
E
R
I
E
A
F
V
A
E
L
K
R
Zebra Danio
Brachydanio rerio
NP_998068
355
39340
T41
S
V
E
T
A
R
E
T
S
S
L
L
R
R
I
Tiger Blowfish
Takifugu rubipres
Q90511
355
39111
T41
S
S
E
T
A
R
E
T
T
A
L
L
R
R
I
Fruit Fly
Dros. melanogaster
NP_570020
352
39136
I39
L
D
I
F
K
Y
I
I
M
S
K
S
W
Q
N
Honey Bee
Apis mellifera
XP_393835
353
39514
A38
I
V
V
A
T
V
V
A
L
K
E
I
I
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202427
304
33432
I16
A
H
S
T
L
S
L
I
R
K
I
I
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32502
381
42551
T44
S
Y
A
I
A
L
E
T
L
Q
L
L
M
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
94.8
N.A.
94
92.8
N.A.
N.A.
84.6
68.3
80.2
79.7
47.7
54.1
N.A.
54.4
Protein Similarity:
100
99.4
99.4
97.1
N.A.
98.2
97.7
N.A.
N.A.
92
77.4
88.1
89
67
70.8
N.A.
69.8
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
66.6
6.6
66.6
66.6
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
13.3
73.3
73.3
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
72
0
0
15
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
29
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
50
36
8
0
0
72
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
43
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
8
8
15
0
0
8
15
8
0
50
% I
% Lys:
0
0
0
0
8
0
0
0
0
15
8
0
0
15
0
% K
% Leu:
8
8
0
0
8
8
8
0
65
0
72
72
8
0
15
% L
% Met:
0
0
0
43
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
0
29
0
% Q
% Arg:
0
0
0
0
8
65
0
0
8
0
0
0
65
43
8
% R
% Ser:
72
8
15
0
0
8
0
0
8
22
0
8
8
0
8
% S
% Thr:
0
0
0
29
8
0
0
72
8
0
0
0
0
0
0
% T
% Val:
0
15
8
0
0
8
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _