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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP153 All Species: 22.42
Human Site: S505 Identified Species: 49.33
UniProt: P49790 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49790 NP_005115.2 1475 153938 S505 S P S P I N S S Q A L T N K V
Chimpanzee Pan troglodytes XP_001170682 1475 154026 S505 S P S P I N S S Q S L T N K V
Rhesus Macaque Macaca mulatta XP_001096101 1474 153680 S505 S P S P I N S S Q S L T N K V
Dog Lupus familis XP_535898 1478 153685 S506 S P A T I S P S Q S L T N K V
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P49791 1468 152805 S505 S S S S V S P S Q P L S N K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508163 1644 167929 Q652 S S P I R M A Q P S A N K V Q
Chicken Gallus gallus XP_418937 1473 153350 S508 S L A P F N F S F L T S S T V
Frog Xenopus laevis NP_001082284 1605 164952 S544 N A Q S P G S S V D F T F S V
Zebra Danio Brachydanio rerio XP_700317 1436 146282 F477 S N F T L P T F T F S T P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793520 1708 174739 S575 K P S P A Q S S S T V P S F K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14907 823 86497
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.2 86.8 N.A. N.A. 81.9 N.A. 62.8 64.5 43.7 43.5 N.A. N.A. N.A. N.A. 26.5
Protein Similarity: 100 99.4 98.3 91.7 N.A. N.A. 88.9 N.A. 72.2 75.6 58.5 57.7 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 93.3 93.3 66.6 N.A. N.A. 53.3 N.A. 6.6 33.3 26.6 13.3 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. N.A. 73.3 N.A. 20 53.3 33.3 26.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 10 0 10 0 0 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 10 0 10 10 10 10 10 0 10 10 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 37 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 10 46 10 % K
% Leu: 0 10 0 0 10 0 0 0 0 10 46 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 37 0 0 0 0 0 10 46 0 0 % N
% Pro: 0 46 10 46 10 10 19 0 10 10 0 10 10 10 10 % P
% Gln: 0 0 10 0 0 10 0 10 46 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 73 19 46 19 0 19 46 73 10 37 10 19 19 10 0 % S
% Thr: 0 0 0 19 0 0 10 0 10 10 10 55 0 10 0 % T
% Val: 0 0 0 0 10 0 0 0 10 0 10 0 0 10 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _