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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP153 All Species: 14.85
Human Site: S518 Identified Species: 32.67
UniProt: P49790 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49790 NP_005115.2 1475 153938 S518 K V Q M T S P S S T G S P M F
Chimpanzee Pan troglodytes XP_001170682 1475 154026 S518 K V Q M T S P S S T G S P M F
Rhesus Macaque Macaca mulatta XP_001096101 1474 153680 S518 K V Q M T S P S S T G S P M F
Dog Lupus familis XP_535898 1478 153685 N519 K V Q M T S P N S T G S P M F
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P49791 1468 152805 G518 K V Q M T S L G S T G N P V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508163 1644 167929 N665 V Q A T P P S N P G S P V F R
Chicken Gallus gallus XP_418937 1473 153350 T521 T V S S P P S T V S T S V M N
Frog Xenopus laevis NP_001082284 1605 164952 S557 S V P A A K A S S A T S D E S
Zebra Danio Brachydanio rerio XP_700317 1436 146282 S490 P P T S S L K S S T A P L I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793520 1708 174739 S588 F K F A S P A S S P E G P Q F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14907 823 86497
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.2 86.8 N.A. N.A. 81.9 N.A. 62.8 64.5 43.7 43.5 N.A. N.A. N.A. N.A. 26.5
Protein Similarity: 100 99.4 98.3 91.7 N.A. N.A. 88.9 N.A. 72.2 75.6 58.5 57.7 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 93.3 N.A. N.A. 73.3 N.A. 0 20 26.6 20 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. N.A. 86.6 N.A. 6.6 33.3 26.6 33.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 10 0 19 0 0 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 10 0 10 0 0 0 0 0 0 0 0 0 0 10 55 % F
% Gly: 0 0 0 0 0 0 0 10 0 10 46 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 46 10 0 0 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 10 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 46 0 0 0 0 0 0 0 0 0 46 0 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 0 10 0 0 10 % N
% Pro: 10 10 10 0 19 28 37 0 10 10 0 19 55 0 0 % P
% Gln: 0 10 46 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 0 10 19 19 46 19 55 73 10 10 55 0 0 10 % S
% Thr: 10 0 10 10 46 0 0 10 0 55 19 0 0 0 10 % T
% Val: 10 64 0 0 0 0 0 0 10 0 0 0 19 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _