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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RGS4 All Species: 23.03
Human Site: S38 Identified Species: 56.3
UniProt: P49798 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49798 NP_005604.1 205 23256 S38 D S C E H N S S H N K K D K V
Chimpanzee Pan troglodytes XP_001174409 193 22096 K29 E H N S S H N K K D K V V I C
Rhesus Macaque Macaca mulatta XP_001082467 302 33977 S135 D S C E H N S S H N K K D K V
Dog Lupus familis XP_545783 205 23310 S38 D S C E H N S S H S K K D R V
Cat Felis silvestris
Mouse Mus musculus O08899 205 23270 S38 D S C E H S S S H S K K D K V
Rat Rattus norvegicus P49799 205 23230 S38 D S C E H S S S H S K K D K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q7SZC6 208 23504 S38 D S C D Y G S S Q G K K E K V
Frog Xenopus laevis A1A643 201 23280 K35 K N F A V P W K N Y L K S M L
Zebra Danio Brachydanio rerio Q6DGI0 174 20503 N10 T R L G C L S N K S D S C S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34295 201 23269 S37 L S Y E M V Y S W Q Q S F D T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 67.8 94.6 N.A. 95.6 97 N.A. N.A. 74 37 40.9 N.A. N.A. N.A. 36.5 N.A.
Protein Similarity: 100 94.1 67.8 97 N.A. 97.5 98.5 N.A. N.A. 86.5 55.1 59 N.A. N.A. N.A. 55.1 N.A.
P-Site Identity: 100 6.6 100 86.6 N.A. 86.6 86.6 N.A. N.A. 60 6.6 6.6 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. N.A. 80 26.6 20 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 60 0 10 0 0 0 0 0 0 0 10 0 10 % C
% Asp: 60 0 0 10 0 0 0 0 0 10 10 0 50 10 10 % D
% Glu: 10 0 0 60 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % G
% His: 0 10 0 0 50 10 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 0 0 20 20 0 70 70 0 50 0 % K
% Leu: 10 0 10 0 0 10 0 0 0 0 10 0 0 0 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 10 0 0 30 10 10 10 20 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 10 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 70 0 10 10 20 70 70 0 40 0 20 10 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 10 0 0 0 0 0 10 10 0 60 % V
% Trp: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 0 10 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _