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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS4
All Species:
16.97
Human Site:
Y174
Identified Species:
41.48
UniProt:
P49798
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49798
NP_005604.1
205
23256
Y174
R
F
L
K
S
R
F
Y
L
D
L
V
N
P
S
Chimpanzee
Pan troglodytes
XP_001174409
193
22096
L163
F
L
K
S
R
F
Y
L
D
L
V
N
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001082467
302
33977
Y271
R
F
L
K
S
R
F
Y
L
D
L
V
N
P
S
Dog
Lupus familis
XP_545783
205
23310
Y174
R
F
L
K
S
R
F
Y
L
D
L
A
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O08899
205
23270
Y174
R
F
L
K
S
R
F
Y
L
D
L
T
N
P
S
Rat
Rattus norvegicus
P49799
205
23230
Y174
R
F
L
K
S
R
F
Y
L
D
L
T
N
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q7SZC6
208
23504
L174
R
F
L
K
S
P
Y
L
D
L
V
S
P
P
R
Frog
Xenopus laevis
A1A643
201
23280
I171
G
A
Q
K
M
I
F
I
L
M
E
R
D
S
Y
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
M144
Q
A
K
V
Y
S
L
M
E
K
D
S
Y
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34295
201
23269
E171
E
M
D
I
G
G
D
E
E
K
E
R
E
Q
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
67.8
94.6
N.A.
95.6
97
N.A.
N.A.
74
37
40.9
N.A.
N.A.
N.A.
36.5
N.A.
Protein Similarity:
100
94.1
67.8
97
N.A.
97.5
98.5
N.A.
N.A.
86.5
55.1
59
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
40
20
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
53.3
26.6
13.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
20
50
10
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
10
20
0
20
0
10
0
0
% E
% Phe:
10
60
0
0
0
10
60
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
70
0
0
0
0
0
20
0
0
0
0
0
% K
% Leu:
0
10
60
0
0
0
10
20
60
20
50
0
0
0
0
% L
% Met:
0
10
0
0
10
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
50
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
20
60
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
60
0
0
0
10
50
0
0
0
0
0
20
0
0
30
% R
% Ser:
0
0
0
10
60
10
0
0
0
0
0
20
0
30
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
20
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
20
50
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _