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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RGS7 All Species: 29.39
Human Site: T245 Identified Species: 49.74
UniProt: P49802 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49802 NP_002915.3 495 57668 T245 R S H S P T H T P T P E T K P
Chimpanzee Pan troglodytes XP_001159739 487 56751 T245 R S H S P T H T P T P E T K P
Rhesus Macaque Macaca mulatta XP_001095075 499 57951 T249 R S H S P T H T P T P E T K P
Dog Lupus familis XP_537503 683 78241 I235 Q S Q S P V H I P S Q P I R K
Cat Felis silvestris
Mouse Mus musculus O54829 469 54704 T245 R S H S P T H T P T P E T K P
Rat Rattus norvegicus P49803 477 55673 T245 R S H S P T H T P T P E T K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514330 608 70692 T245 R S H S P T H T P L P E T K P
Chicken Gallus gallus XP_419551 506 58927 T245 R S H S P T H T P V P E T K P
Frog Xenopus laevis NP_001079945 471 54554 M247 Q S Q S P V H M A S H V I R K
Zebra Danio Brachydanio rerio NP_001002541 459 53605 H224 S S R M K N P H K T R K S V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523380 647 70137 S422 G S S H G T G S A G A S L A K
Honey Bee Apis mellifera XP_393403 510 59946 S288 M A N T D I P S H S E S Y T V
Nematode Worm Caenorhab. elegans P49809 555 63260 Y245 S G I G C T Q Y S Q S V A A A
Sea Urchin Strong. purpuratus XP_782272 467 54702 C236 S P E D G D R C P S D S D I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 98.8 51 N.A. 91.3 95.1 N.A. 76.8 87.7 70.3 83 N.A. 41.2 53.5 34.5 56.1
Protein Similarity: 100 96.7 98.8 61.9 N.A. 93.7 96.1 N.A. 79.2 91.9 81.8 87.8 N.A. 53.7 71.9 51.1 71.9
P-Site Identity: 100 100 100 33.3 N.A. 100 100 N.A. 93.3 93.3 26.6 13.3 N.A. 13.3 0 6.6 6.6
P-Site Similarity: 100 100 100 53.3 N.A. 100 100 N.A. 93.3 93.3 46.6 26.6 N.A. 20 33.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 15 0 8 0 8 15 8 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 0 0 0 8 0 8 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 8 50 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 8 15 0 8 0 0 8 0 0 0 0 0 % G
% His: 0 0 50 8 0 0 65 8 8 0 8 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 8 0 0 0 0 15 8 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 0 0 8 0 50 22 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % L
% Met: 8 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 65 0 15 0 65 0 50 8 0 0 50 % P
% Gln: 15 0 15 0 0 0 8 0 0 8 8 0 0 0 8 % Q
% Arg: 50 0 8 0 0 0 8 0 0 0 8 0 0 15 0 % R
% Ser: 22 79 8 65 0 0 0 15 8 29 8 22 8 0 0 % S
% Thr: 0 0 0 8 0 65 0 50 0 43 0 0 50 8 0 % T
% Val: 0 0 0 0 0 15 0 0 0 8 0 15 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _