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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS7
All Species:
17.27
Human Site:
T462
Identified Species:
29.23
UniProt:
P49802
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49802
NP_002915.3
495
57668
T462
G
N
S
M
D
R
R
T
S
F
E
K
F
A
Q
Chimpanzee
Pan troglodytes
XP_001159739
487
56751
T462
G
N
S
M
D
R
R
T
S
F
E
K
F
A
Q
Rhesus Macaque
Macaca mulatta
XP_001095075
499
57951
T466
G
N
S
M
D
R
R
T
S
F
E
K
F
A
Q
Dog
Lupus familis
XP_537503
683
78241
T452
G
S
A
Q
G
F
R
T
G
S
D
A
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O54829
469
54704
I439
S
D
S
Y
P
R
F
I
R
S
S
A
Y
Q
E
Rat
Rattus norvegicus
P49803
477
55673
L447
R
S
S
A
Y
Q
E
L
L
Q
A
K
R
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514330
608
70692
T462
E
N
S
M
D
R
R
T
S
F
E
K
F
T
R
Chicken
Gallus gallus
XP_419551
506
58927
R462
G
T
P
H
S
F
F
R
G
A
R
N
H
L
E
Frog
Xenopus laevis
NP_001079945
471
54554
L441
S
D
S
Y
A
R
F
L
R
S
N
A
Y
Q
D
Zebra Danio
Brachydanio rerio
NP_001002541
459
53605
D433
I
Y
K
L
M
K
S
D
S
Y
N
R
F
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523380
647
70137
S617
L
M
K
S
D
S
Y
S
R
Y
L
R
S
D
M
Honey Bee
Apis mellifera
XP_393403
510
59946
S485
S
Y
S
R
Y
L
R
S
E
M
Y
K
D
F
L
Nematode Worm
Caenorhab. elegans
P49809
555
63260
K501
E
V
T
E
D
N
L
K
N
P
N
R
W
S
F
Sea Urchin
Strong. purpuratus
XP_782272
467
54702
R434
D
S
Y
P
R
F
L
R
S
E
Q
Y
K
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
98.8
51
N.A.
91.3
95.1
N.A.
76.8
87.7
70.3
83
N.A.
41.2
53.5
34.5
56.1
Protein Similarity:
100
96.7
98.8
61.9
N.A.
93.7
96.1
N.A.
79.2
91.9
81.8
87.8
N.A.
53.7
71.9
51.1
71.9
P-Site Identity:
100
100
100
20
N.A.
13.3
13.3
N.A.
80
6.6
13.3
13.3
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
100
100
40
N.A.
33.3
26.6
N.A.
86.6
13.3
26.6
46.6
N.A.
26.6
26.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
8
8
22
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
43
0
0
8
0
0
8
0
8
8
8
% D
% Glu:
15
0
0
8
0
0
8
0
8
8
29
0
0
15
15
% E
% Phe:
0
0
0
0
0
22
22
0
0
29
0
0
36
8
8
% F
% Gly:
36
0
0
0
8
0
0
0
15
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
15
0
0
8
0
8
0
0
0
43
8
8
0
% K
% Leu:
8
0
0
8
0
8
15
15
8
0
8
0
0
8
15
% L
% Met:
0
8
0
29
8
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
29
0
0
0
8
0
0
8
0
22
8
0
0
0
% N
% Pro:
0
0
8
8
8
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
8
8
0
0
15
22
% Q
% Arg:
8
0
0
8
8
43
43
15
22
0
8
22
8
0
15
% R
% Ser:
22
22
58
8
8
8
8
15
43
22
8
0
15
8
8
% S
% Thr:
0
8
8
0
0
0
0
36
0
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
15
8
15
15
0
8
0
0
15
8
8
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _