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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAF6 All Species: 18.79
Human Site: S405 Identified Species: 34.44
UniProt: P49848 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49848 NP_005632.1 677 72668 S405 Q E G E R I R S V L D G P V L
Chimpanzee Pan troglodytes XP_001139475 512 56014 Y253 I A T D P G L Y Q M L P R F S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546964 678 72657 S405 Q E G E R I R S V L D G P V L
Cat Felis silvestris
Mouse Mus musculus Q62311 678 72655 S405 Q E G E R I R S V L D G P V L
Rat Rattus norvegicus Q63801 678 72695 S405 Q E G E R I R S V L D G P V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520250 389 43457 V130 P Q T S L D V V L K A H W L S
Chicken Gallus gallus
Frog Xenopus laevis Q91857 618 66839 D359 F T K T W V D D R T P W T T R
Zebra Danio Brachydanio rerio NP_001004557 636 69179 V377 L A E L G H D V I K T L I I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49847 606 65636 Q347 N T L T N N L Q T R V T R I F
Honey Bee Apis mellifera XP_393233 629 68791 I369 L A S L Y G A I E G L C E L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781123 657 70977 T384 L G P E V M K T L V I P K V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_171987 549 61346 S290 D F A A N L V S L I C K R Y G
Baker's Yeast Sacchar. cerevisiae P53040 516 57883 T257 A A L T S L R T D S G L H Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.4 N.A. 98 N.A. 97.4 97.4 N.A. 34.1 N.A. 73.4 68.6 N.A. 43.8 45 N.A. 46.6
Protein Similarity: 100 75.4 N.A. 98.3 N.A. 97.7 97.7 N.A. 43.5 N.A. 81.5 79.1 N.A. 61.8 63.2 N.A. 62.6
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. 0 N.A. 0 0 N.A. 0 0 N.A. 13.3
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. 20 N.A. 6.6 13.3 N.A. 6.6 6.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 32 24.5 N.A.
Protein Similarity: N.A. N.A. N.A. 48.4 39.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 31 8 8 0 0 8 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 8 0 0 8 0 8 16 8 8 0 31 0 0 0 0 % D
% Glu: 0 31 8 39 0 0 0 0 8 0 0 0 8 0 0 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 0 0 0 8 8 % F
% Gly: 0 8 31 0 8 16 0 0 0 8 8 31 0 0 16 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % H
% Ile: 8 0 0 0 0 31 0 8 8 8 8 0 8 16 0 % I
% Lys: 0 0 8 0 0 0 8 0 0 16 0 8 8 0 0 % K
% Leu: 24 0 16 16 8 16 16 0 24 31 16 16 0 16 39 % L
% Met: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 0 0 0 16 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 0 8 0 0 0 0 0 8 16 31 0 8 % P
% Gln: 31 8 0 0 0 0 0 8 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 31 0 39 0 8 8 0 0 24 0 16 % R
% Ser: 0 0 8 8 8 0 0 39 0 8 0 0 0 0 16 % S
% Thr: 0 16 16 24 0 0 0 16 8 8 8 8 8 8 0 % T
% Val: 0 0 0 0 8 8 16 16 31 8 8 0 0 39 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 8 0 0 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _