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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5C2
All Species:
37.27
Human Site:
Y225
Identified Species:
82
UniProt:
P49902
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49902
NP_001127845.1
561
64970
Y225
T
V
E
N
L
E
K
Y
V
V
K
D
G
K
L
Chimpanzee
Pan troglodytes
XP_001172474
559
64693
Y225
T
V
E
N
L
E
K
Y
V
V
K
D
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001113556
370
42717
R47
K
L
P
L
L
L
S
R
M
K
E
V
G
K
V
Dog
Lupus familis
XP_535002
561
64951
Y225
T
V
E
N
L
E
K
Y
V
V
K
D
G
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1L4
560
64790
Y225
T
V
E
N
L
E
K
Y
V
V
K
D
G
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511914
655
75478
Y225
T
V
E
N
L
E
K
Y
V
V
K
D
G
K
L
Chicken
Gallus gallus
Q5ZIZ4
569
65876
Y225
T
L
E
N
L
E
K
Y
V
V
K
D
G
K
L
Frog
Xenopus laevis
Q6DKB0
569
66161
Y225
T
V
E
N
L
P
K
Y
V
V
K
D
S
K
L
Zebra Danio
Brachydanio rerio
NP_001073435
562
65048
Y226
T
V
E
N
P
E
K
Y
V
V
K
D
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996510
715
81556
Y352
T
T
Q
N
M
A
H
Y
V
K
K
D
E
R
L
Honey Bee
Apis mellifera
XP_624160
566
65529
Y216
T
M
E
N
L
D
L
Y
V
K
K
D
R
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.9
99.2
N.A.
99.2
N.A.
N.A.
76.9
94
91.2
89.6
N.A.
48.5
60
N.A.
N.A.
Protein Similarity:
100
99.6
65.9
100
N.A.
99.8
N.A.
N.A.
79.6
96.4
94.9
93.9
N.A.
59.4
76.1
N.A.
N.A.
P-Site Identity:
100
100
20
100
N.A.
100
N.A.
N.A.
100
93.3
86.6
86.6
N.A.
46.6
60
N.A.
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
100
N.A.
N.A.
100
100
86.6
86.6
N.A.
66.6
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
91
0
0
0
% D
% Glu:
0
0
82
0
0
64
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
73
0
0
28
91
0
0
82
0
% K
% Leu:
0
19
0
10
82
10
10
0
0
0
0
0
0
0
91
% L
% Met:
0
10
0
0
10
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
10
19
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% S
% Thr:
91
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
64
0
0
0
0
0
0
91
73
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _