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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPHS1
All Species:
36.06
Human Site:
S158
Identified Species:
72.12
UniProt:
P49903
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49903
NP_036379.2
392
42911
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Chimpanzee
Pan troglodytes
NP_001108203
448
47195
A209
A
A
E
E
G
G
T
A
V
T
G
G
Q
T
V
Rhesus Macaque
Macaca mulatta
NP_001152892
451
47421
A212
A
A
E
E
G
G
T
A
V
T
G
G
Q
T
V
Dog
Lupus familis
XP_848867
392
42906
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH69
392
42888
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Rat
Rattus norvegicus
NP_001098100
392
42874
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507943
392
42888
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Chicken
Gallus gallus
NP_001157556
392
42904
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Frog
Xenopus laevis
Q6PF47
392
42828
S158
A
A
E
E
A
G
T
S
V
T
G
G
Q
T
V
Zebra Danio
Brachydanio rerio
Q7ZW38
392
42904
S158
A
S
E
E
A
G
T
S
V
T
G
G
Q
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18373
398
43428
T180
S
A
L
E
A
G
T
T
V
T
G
G
Q
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62461
378
41537
K154
A
A
D
E
A
G
T
K
I
R
G
G
Q
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.5
66
99.7
N.A.
99.4
99.4
N.A.
99.2
99.4
98.4
96.6
N.A.
69
N.A.
50.5
N.A.
Protein Similarity:
100
76.3
75.8
100
N.A.
100
100
N.A.
99.7
99.7
99.4
99.2
N.A.
81.6
N.A.
67
N.A.
P-Site Identity:
100
86.6
86.6
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
73.3
N.A.
73.3
N.A.
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
92
92
0
0
84
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
84
100
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
100
0
0
0
0
100
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
0
0
67
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
100
9
0
92
0
0
0
92
0
% T
% Val:
0
0
0
0
0
0
0
0
92
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _