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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPP1
All Species:
15.45
Human Site:
S190
Identified Species:
48.57
UniProt:
P49908
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49908
NP_001078955.1
381
43174
S190
E
D
F
C
K
R
V
S
L
A
T
V
D
K
T
Chimpanzee
Pan troglodytes
NP_001108587
381
41693
S190
E
D
F
C
K
R
V
S
L
A
T
V
D
K
T
Rhesus Macaque
Macaca mulatta
NP_001152962
381
41272
S190
E
D
F
C
K
S
V
S
L
A
T
V
D
E
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70274
380
41187
T190
E
D
F
C
K
T
V
T
S
A
T
A
N
K
T
Rat
Rattus norvegicus
P25236
385
41564
S190
E
A
F
C
K
N
V
S
S
A
T
A
S
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026780
393
42693
G195
K
E
D
E
N
L
A
G
I
E
P
E
P
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q98SV1
367
39399
E190
E
E
C
K
K
A
T
E
E
V
N
K
P
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199348
206
23025
W41
R
C
M
E
P
P
S
W
S
L
R
G
R
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
92.6
N.A.
N.A.
71.9
72.4
N.A.
N.A.
51.6
N.A.
37
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
96.3
92.6
N.A.
N.A.
80.5
79.2
N.A.
N.A.
63
N.A.
50.3
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
100
100
86.6
N.A.
N.A.
66.6
66.6
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
80
66.6
N.A.
N.A.
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
13
13
0
0
63
0
25
0
0
0
% A
% Cys:
0
13
13
63
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
13
0
0
0
0
0
0
0
0
0
38
0
0
% D
% Glu:
75
25
0
25
0
0
0
13
13
13
0
13
0
25
13
% E
% Phe:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
13
0
0
13
75
0
0
0
0
0
0
13
0
50
0
% K
% Leu:
0
0
0
0
0
13
0
0
38
13
0
0
0
0
0
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
13
0
0
0
0
13
0
13
0
0
% N
% Pro:
0
0
0
0
13
13
0
0
0
0
13
0
25
0
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
25
0
0
0
0
13
0
13
0
0
% R
% Ser:
0
0
0
0
0
13
13
50
38
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
13
13
13
0
0
63
0
0
0
63
% T
% Val:
0
0
0
0
0
0
63
0
0
13
0
38
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _