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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMPS All Species: 20.3
Human Site: S132 Identified Species: 49.63
UniProt: P49915 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49915 NP_003866.1 693 76715 S132 E D G V F N I S V D N T C S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105046 693 76701 S132 E D G V F N I S V D N T C S L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3THK7 693 76705 S132 E D G V F N I S M D N T C S L
Rat Rattus norvegicus Q4V7C6 693 76739 S132 E D G V F N I S M D N T C S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512299 631 69806 T134 F H P E V G L T K N G K V I L
Chicken Gallus gallus NP_001006556 693 76616 T132 E D G V F N I T L D N T C S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956881 692 76917 A131 E D G V F N I A L D N S C S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_620114 683 76772 S132 E T S C P L F S R L S R T Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09580 792 88052 Q213 E D G A C E I Q V D T S V H L
Sea Urchin Strong. purpuratus XP_783757 684 75195 R131 D P S V S L Y R G L D K Q Q N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 N.A. N.A. 97.9 97.9 N.A. 87.7 94.5 N.A. 86.8 N.A. 58 N.A. 46.3 64.9
Protein Similarity: 100 N.A. 100 N.A. N.A. 99.2 99.1 N.A. 90.7 98.2 N.A. 94.6 N.A. 75.1 N.A. 61.3 80.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 93.3 93.3 N.A. 6.6 86.6 N.A. 80 N.A. 13.3 N.A. 46.6 6.6
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 26.6 100 N.A. 100 N.A. 20 N.A. 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 60 0 0 % C
% Asp: 10 70 0 0 0 0 0 0 0 70 10 0 0 0 0 % D
% Glu: 80 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 60 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 70 0 0 10 0 0 10 0 10 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 70 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 20 0 0 0 % K
% Leu: 0 0 0 0 0 20 10 0 20 20 0 0 0 0 80 % L
% Met: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 60 0 0 0 10 60 0 0 0 10 % N
% Pro: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 20 0 % Q
% Arg: 0 0 0 0 0 0 0 10 10 0 0 10 0 0 0 % R
% Ser: 0 0 20 0 10 0 0 50 0 0 10 20 0 60 10 % S
% Thr: 0 10 0 0 0 0 0 20 0 0 10 50 10 0 0 % T
% Val: 0 0 0 70 10 0 0 0 30 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _