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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMPS All Species: 22.73
Human Site: T481 Identified Species: 55.56
UniProt: P49915 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49915 NP_003866.1 693 76715 T481 A S V K K P H T L L Q R V K A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105046 693 76701 T481 A S V K K P H T L L Q R V K A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3THK7 693 76705 T481 A S V K K P H T L L Q R V K A
Rat Rattus norvegicus Q4V7C6 693 76739 T481 A S V K K P H T L L Q R V K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512299 631 69806 V424 P H T L L Q R V K A C T T E E
Chicken Gallus gallus NP_001006556 693 76616 T481 A S V K K P H T L L Q R V K A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956881 692 76917 T480 A S V K K P H T L L Q R V K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_620114 683 76772 A470 N K L Q K N H A L I N R V T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09580 792 88052 F569 G I Y E H L Q F E Q A R N N V
Sea Urchin Strong. purpuratus XP_783757 684 75195 A471 E S M D K P H A L A S K I S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 N.A. N.A. 97.9 97.9 N.A. 87.7 94.5 N.A. 86.8 N.A. 58 N.A. 46.3 64.9
Protein Similarity: 100 N.A. 100 N.A. N.A. 99.2 99.1 N.A. 90.7 98.2 N.A. 94.6 N.A. 75.1 N.A. 61.3 80.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 0 100 N.A. 93.3 N.A. 40 N.A. 6.6 33.3
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 60 N.A. 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 0 0 0 0 0 20 0 20 10 0 0 0 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 10 0 0 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 10 0 80 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 10 0 0 10 0 0 % I
% Lys: 0 10 0 60 80 0 0 0 10 0 0 10 0 60 0 % K
% Leu: 0 0 10 10 10 10 0 0 80 60 0 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 0 10 0 10 10 0 % N
% Pro: 10 0 0 0 0 70 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 10 10 0 0 10 60 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 80 0 0 0 % R
% Ser: 0 70 0 0 0 0 0 0 0 0 10 0 0 10 20 % S
% Thr: 0 0 10 0 0 0 0 60 0 0 0 10 10 10 0 % T
% Val: 0 0 60 0 0 0 0 10 0 0 0 0 70 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _