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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 17.27
Human Site: S39 Identified Species: 31.67
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 S39 V R Q F S Q W S E T D L L H G
Chimpanzee Pan troglodytes XP_511409 922 102716 V35 G V C R I G K V V P N P F S E
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 S39 V R Q F S Q W S E T D L L H G
Dog Lupus familis XP_548265 991 110592 S40 I R Q F S H W S E R G L L H G
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 S40 I S Q F S Q W S E T N L L G G
Rat Rattus norvegicus NP_001012011 943 105425 S40 I R Q F S Q W S E T N L L C G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 T15 V D Y A K R G T A G C K K C K
Frog Xenopus laevis NP_001082183 988 110688 P35 T V L A R W S P S P L R S A L
Zebra Danio Brachydanio rerio NP_001025345 752 84159
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292
Sea Urchin Strong. purpuratus XP_786357 875 97201
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 0 100 73.3 N.A. 73.3 80 N.A. N.A. 6.6 0 0 N.A. 0 N.A. 0 0
P-Site Similarity: 100 6.6 100 80 N.A. 86.6 93.3 N.A. N.A. 20 0 0 N.A. 0 N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 0 8 0 0 0 0 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 8 0 0 16 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 16 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 39 0 0 0 0 0 8 % E
% Phe: 0 0 0 39 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 0 0 0 8 8 0 0 8 8 0 0 8 39 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 24 0 % H
% Ile: 24 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 0 0 0 8 8 0 8 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 8 39 39 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 16 0 8 0 0 0 % P
% Gln: 0 0 39 0 0 31 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 31 0 8 8 8 0 0 0 8 0 8 0 0 0 % R
% Ser: 0 8 0 0 39 0 8 39 8 0 0 0 8 8 0 % S
% Thr: 8 0 0 0 0 0 0 8 0 31 0 0 0 0 0 % T
% Val: 24 16 0 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 39 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _