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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 9.09
Human Site: S889 Identified Species: 16.67
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 S889 G K L S N S N S K D G N M Q T
Chimpanzee Pan troglodytes XP_511409 922 102716 P812 G N M Q T A K P S T M K V G E
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 S889 G K L S N S N S K G G N M L T
Dog Lupus familis XP_548265 991 110592 K871 S G P A G A S K A K K V G G R
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 S894 E Q K L N S P S S R G G I K P
Rat Rattus norvegicus NP_001012011 943 105425 Q832 P Q L K E L Y Q L S K D K A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 K792 K S P A K A K K P E G T K A V
Frog Xenopus laevis NP_001082183 988 110688 S851 S P A K G K T S E S S K L P P
Zebra Danio Brachydanio rerio NP_001025345 752 84159 C642 K W C T V T K C S G G F D D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 S696 K P S K E F K S V V K K E P K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292 P663 E G S S K E N P V K E E I K K
Sea Urchin Strong. purpuratus XP_786357 875 97201 S765 L G V Q S S P S K V S A K R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 C645 D T G E F E T C C K I G T G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 6.6 86.6 0 N.A. 26.6 6.6 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 N.A. 13.3 20
P-Site Similarity: 100 26.6 86.6 20 N.A. 46.6 20 N.A. N.A. 26.6 20 20 N.A. 6.6 N.A. 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 0 24 0 0 8 0 0 8 0 16 8 % A
% Cys: 0 0 8 0 0 0 0 16 8 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 8 0 8 8 8 8 % D
% Glu: 16 0 0 8 16 16 0 0 8 8 8 8 8 0 8 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 8 % F
% Gly: 24 24 8 0 16 0 0 0 0 16 39 16 8 24 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 16 0 0 % I
% Lys: 24 16 8 24 16 8 31 16 24 24 24 24 24 16 24 % K
% Leu: 8 0 24 8 0 8 0 0 8 0 0 0 8 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 8 0 16 0 0 % M
% Asn: 0 8 0 0 24 0 24 0 0 0 0 16 0 0 0 % N
% Pro: 8 16 16 0 0 0 16 16 8 0 0 0 0 16 16 % P
% Gln: 0 16 0 16 0 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % R
% Ser: 16 8 16 24 8 31 8 47 24 16 16 0 0 0 0 % S
% Thr: 0 8 0 8 8 8 16 0 0 8 0 8 8 0 16 % T
% Val: 0 0 8 0 8 0 0 0 16 16 0 8 8 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _