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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 1.52
Human Site: T910 Identified Species: 2.78
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 T910 K V G E K L A T K S S P V K V
Chimpanzee Pan troglodytes XP_511409 922 102716 K833 S P V K V G E K R K A A D E T
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 M910 K V G E K L A M K S S P V K V
Dog Lupus familis XP_548265 991 110592 A892 R G G H K L I A K P S P V K V
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 A915 M K P G E K L A V K S S P V K
Rat Rattus norvegicus NP_001012011 943 105425 G853 D E G S S T T G G S N G E N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 K813 P E E K R G E K R K A S E V E
Frog Xenopus laevis NP_001082183 988 110688 K872 P M K A E K R K S H T P T T V
Zebra Danio Brachydanio rerio NP_001025345 752 84159 I663 K D L D V I K I G K D P S K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 Q717 E S T S S K P Q L F E G L V A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292 K684 S P K K F E K K P P V K S S P
Sea Urchin Strong. purpuratus XP_786357 875 97201 T786 D D D E E E I T G F S F G K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 P666 L L H D R L T P T I I D G P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 0 93.3 60 N.A. 6.6 13.3 N.A. N.A. 0 13.3 20 N.A. 0 N.A. 0 26.6
P-Site Similarity: 100 26.6 93.3 66.6 N.A. 13.3 20 N.A. N.A. 26.6 33.3 40 N.A. 13.3 N.A. 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 16 16 0 0 16 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 16 8 16 0 0 0 0 0 0 8 8 8 0 0 % D
% Glu: 8 16 8 24 24 16 16 0 0 0 8 0 16 8 16 % E
% Phe: 0 0 0 0 8 0 0 0 0 16 0 8 0 0 0 % F
% Gly: 0 8 31 8 0 16 0 8 24 0 0 16 16 0 8 % G
% His: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 16 8 0 8 8 0 0 0 8 % I
% Lys: 24 8 16 24 24 24 16 31 24 31 0 8 0 39 16 % K
% Leu: 8 8 8 0 0 31 8 0 8 0 0 0 8 0 0 % L
% Met: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 16 16 8 0 0 0 8 8 8 16 0 39 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 16 0 8 0 16 0 0 0 0 0 0 % R
% Ser: 16 8 0 16 16 0 0 0 8 24 39 16 16 8 0 % S
% Thr: 0 0 8 0 0 8 16 16 8 0 8 0 8 8 8 % T
% Val: 0 16 8 0 16 0 0 0 8 0 8 0 24 24 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _