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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 8.48
Human Site: T976 Identified Species: 15.56
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 T976 E F D M T S A T H V L G S R D
Chimpanzee Pan troglodytes XP_511409 922 102716 P899 L G S R D K N P A A Q Q V S P
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 T976 E F D M T S A T H V L G S R D
Dog Lupus familis XP_548265 991 110592 T958 E F D M A S A T H V L G S G D
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 A981 Q E F D M G S A T H V L G N R
Rat Rattus norvegicus NP_001012011 943 105425 E919 M K R K A A D E T P G L T K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 P879 I G D I D E N P G A K R V S P
Frog Xenopus laevis NP_001082183 988 110688 D938 Y F I A F D G D L V P E Y D L
Zebra Danio Brachydanio rerio NP_001025345 752 84159 G729 E C V M T R T G R R Q L T F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 V783 R S C R H L N V S W L Q S C L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292 E750 S D S D E S D E E T S T N K K
Sea Urchin Strong. purpuratus XP_786357 875 97201 D852 D C Y Q K S K D H V E K F R H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 K732 F L R I R E D K G V E D A T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 0 100 86.6 N.A. 0 0 N.A. N.A. 6.6 13.3 20 N.A. 13.3 N.A. 6.6 26.6
P-Site Similarity: 100 0 100 86.6 N.A. 20 20 N.A. N.A. 13.3 13.3 26.6 N.A. 13.3 N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 16 8 24 8 8 16 0 0 8 0 0 % A
% Cys: 0 16 8 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 8 31 16 16 8 24 16 0 0 0 8 0 8 24 % D
% Glu: 31 8 0 0 8 16 0 16 8 0 16 8 0 0 0 % E
% Phe: 8 31 8 0 8 0 0 0 0 0 0 0 8 8 0 % F
% Gly: 0 16 0 0 0 8 8 8 16 0 8 24 8 8 0 % G
% His: 0 0 0 0 8 0 0 0 31 8 0 0 0 0 8 % H
% Ile: 8 0 8 16 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 8 8 8 8 0 0 8 8 0 16 8 % K
% Leu: 8 8 0 0 0 8 0 0 8 0 31 24 0 0 16 % L
% Met: 8 0 0 31 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 24 0 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 16 0 8 8 0 0 0 16 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 16 16 0 0 0 % Q
% Arg: 8 0 16 16 8 8 0 0 8 8 0 8 0 24 16 % R
% Ser: 8 8 16 0 0 39 8 0 8 0 8 0 31 16 16 % S
% Thr: 0 0 0 0 24 0 8 24 16 8 0 8 16 8 0 % T
% Val: 0 0 8 0 0 0 0 8 0 47 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _