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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
37.27
Human Site:
S310
Identified Species:
58.57
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S310
G
A
S
P
T
E
G
S
L
T
P
F
I
H
N
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S310
G
A
S
S
T
E
G
S
L
T
P
F
I
H
N
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
L96
L
A
K
L
Y
I
E
L
L
N
L
P
R
D
G
Dog
Lupus familis
XP_542663
911
104163
S310
G
D
S
P
R
E
G
S
L
T
P
F
I
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S310
G
E
S
P
Q
E
G
S
L
T
P
F
I
H
N
Rat
Rattus norvegicus
NP_001099565
911
104477
S310
G
E
S
P
Q
E
G
S
L
T
P
F
I
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
S315
G
A
S
P
V
D
G
S
L
T
P
F
I
H
N
Frog
Xenopus laevis
NP_001081114
911
104084
S315
G
A
S
P
L
E
G
S
L
T
P
Y
V
H
N
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
S315
G
A
S
P
L
E
G
S
L
T
P
Y
I
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
T319
G
H
S
Y
D
H
G
T
L
T
P
K
L
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
S347
G
K
S
P
M
E
G
S
L
T
P
Y
I
A
N
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
V298
H
G
M
S
D
I
I
V
Q
N
V
L
D
E
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
V290
H
A
M
S
D
L
I
V
Q
N
I
L
V
D
K
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
T321
G
A
S
L
S
S
G
T
I
S
Q
H
L
R
F
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
Q371
G
E
S
L
G
D
E
Q
S
A
L
T
R
H
L
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
93.3
13.3
80
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
80
N.A.
40
N.A.
N.A.
73.3
P-Site Similarity:
100
93.3
13.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
93.3
93.3
86.6
N.A.
53.3
N.A.
N.A.
80
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
0
N.A.
N.A.
6.6
26.6
20
P-Site Similarity:
0
N.A.
N.A.
13.3
60
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
0
0
0
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
20
14
0
0
0
0
0
0
7
14
0
% D
% Glu:
0
20
0
0
0
54
14
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
7
% F
% Gly:
80
7
0
0
7
0
74
0
0
0
0
0
0
0
14
% G
% His:
14
7
0
0
0
7
0
0
0
0
0
7
0
60
0
% H
% Ile:
0
0
0
0
0
14
14
0
7
0
7
0
54
0
0
% I
% Lys:
0
7
7
0
0
0
0
0
0
0
0
7
0
0
7
% K
% Leu:
7
0
0
20
14
7
0
7
74
0
14
14
14
0
7
% L
% Met:
0
0
14
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
47
% N
% Pro:
0
0
0
54
0
0
0
0
0
0
67
7
0
0
0
% P
% Gln:
0
0
0
0
14
0
0
7
14
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
14
14
7
% R
% Ser:
0
0
80
20
7
7
0
60
7
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
14
0
0
14
0
67
0
7
0
0
7
% T
% Val:
0
0
0
0
7
0
0
14
0
0
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _