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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
46.67
Human Site:
S436
Identified Species:
73.33
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S436
I
M
V
K
Q
P
L
S
I
Y
K
P
D
K
R
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S436
I
M
V
K
Q
P
L
S
I
Y
K
P
D
K
R
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
Q201
L
K
L
G
V
S
Q
Q
T
I
F
S
V
F
H
Dog
Lupus familis
XP_542663
911
104163
S436
I
M
I
K
H
P
L
S
I
Y
K
P
D
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S436
I
M
V
K
H
P
L
S
I
Y
K
P
D
K
R
Rat
Rattus norvegicus
NP_001099565
911
104477
S436
I
M
V
K
H
P
L
S
I
Y
K
P
D
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
S441
I
M
V
K
D
P
M
S
T
Y
K
P
D
K
R
Frog
Xenopus laevis
NP_001081114
911
104084
S441
I
M
V
K
D
P
M
S
I
Y
K
P
D
K
R
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
S441
I
M
V
K
D
P
M
S
I
Y
K
P
D
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
S445
I
V
L
K
K
Q
G
S
R
Y
Q
P
G
V
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
S473
I
V
V
K
H
P
E
S
T
Y
R
P
D
K
R
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
S435
I
V
L
K
D
L
G
S
K
W
E
P
S
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
S427
I
V
L
K
D
L
E
S
K
W
E
P
G
D
R
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
S451
V
V
L
K
Y
Y
N
S
S
Y
N
V
A
S
R
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
S503
L
V
L
K
N
P
R
S
R
Y
S
L
N
S
R
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
86.6
N.A.
93.3
93.3
N.A.
N.A.
80
86.6
86.6
N.A.
40
N.A.
N.A.
66.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
93.3
93.3
N.A.
66.6
N.A.
N.A.
80
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
33.3
N.A.
N.A.
33.3
26.6
33.3
P-Site Similarity:
60
N.A.
N.A.
60
46.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
0
0
0
0
0
60
14
0
% D
% Glu:
0
0
0
0
0
0
14
0
0
0
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% F
% Gly:
0
0
0
7
0
0
14
0
0
0
0
0
14
0
0
% G
% His:
0
0
0
0
27
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
80
0
7
0
0
0
0
0
47
7
0
0
0
0
0
% I
% Lys:
0
7
0
94
7
0
0
0
14
0
54
0
0
60
0
% K
% Leu:
14
0
40
0
0
14
34
0
0
0
0
7
0
0
0
% L
% Met:
0
54
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
80
0
0
0
% P
% Gln:
0
0
0
0
14
7
7
7
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
14
0
7
0
0
0
94
% R
% Ser:
0
0
0
0
0
7
0
94
7
0
7
7
7
14
0
% S
% Thr:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% T
% Val:
7
40
54
0
7
0
0
0
0
0
0
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
80
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _