KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
32.42
Human Site:
S508
Identified Species:
50.95
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S508
H
T
L
S
R
V
G
S
G
C
T
M
K
E
L
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S508
H
T
L
S
R
V
G
S
G
C
T
M
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
I270
M
K
H
Q
S
F
Y
I
E
T
K
L
D
G
E
Dog
Lupus familis
XP_542663
911
104163
S508
H
T
L
C
R
V
G
S
G
Y
T
M
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S508
H
T
L
C
R
V
G
S
G
Y
T
M
K
E
L
Rat
Rattus norvegicus
NP_001099565
911
104477
S508
H
T
L
C
R
V
G
S
G
Y
T
M
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
S513
H
S
I
C
R
V
G
S
G
Y
T
M
K
E
L
Frog
Xenopus laevis
NP_001081114
911
104084
S513
H
S
I
C
R
V
G
S
G
Y
T
M
K
E
L
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
S513
H
T
L
C
R
I
G
S
G
Y
T
L
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
T519
I
G
V
V
A
N
N
T
K
Q
R
G
V
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
S546
Y
S
F
C
K
V
G
S
G
Y
T
L
Q
E
L
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
L513
N
G
L
S
D
E
E
L
D
T
V
V
S
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
L505
T
G
L
S
D
D
E
L
N
T
V
V
S
K
L
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
N542
L
S
F
C
S
I
A
N
G
I
S
Q
E
E
F
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
Y586
G
G
F
K
A
E
D
Y
A
E
I
R
H
H
T
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
73.3
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
86.6
86.6
N.A.
13.3
N.A.
N.A.
80
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
20
N.A.
N.A.
20
13.3
0
P-Site Similarity:
40
N.A.
N.A.
33.3
46.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
54
0
0
0
0
0
14
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
7
7
0
7
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
14
14
0
7
7
0
0
7
67
7
% E
% Phe:
0
0
20
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
27
0
0
0
0
60
0
67
0
0
7
0
7
0
% G
% His:
54
0
7
0
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
7
0
14
0
0
14
0
7
0
7
7
0
0
0
0
% I
% Lys:
0
7
0
7
7
0
0
0
7
0
7
0
54
14
0
% K
% Leu:
7
0
54
0
0
0
0
14
0
0
0
20
0
7
74
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% M
% Asn:
7
0
0
0
0
7
7
7
7
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
7
0
7
7
0
0
% Q
% Arg:
0
0
0
0
54
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
0
27
0
27
14
0
0
60
0
0
7
0
14
0
0
% S
% Thr:
7
40
0
0
0
0
0
7
0
20
60
0
0
0
7
% T
% Val:
0
0
7
7
0
54
0
0
0
0
14
14
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
7
0
47
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _