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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
16.67
Human Site:
S537
Identified Species:
26.19
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S537
H
R
K
A
P
P
S
S
I
L
C
G
T
E
K
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S537
H
R
K
A
P
P
S
S
I
L
C
G
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
T299
S
R
N
G
Y
N
Y
T
D
Q
F
G
A
S
P
Dog
Lupus familis
XP_542663
911
104163
S537
H
K
K
A
L
P
S
S
I
L
C
G
T
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S537
H
K
K
S
P
P
S
S
I
L
C
G
T
E
K
Rat
Rattus norvegicus
NP_001099565
911
104477
C537
Q
R
K
S
P
P
S
C
I
L
C
G
T
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
N542
N
R
K
D
P
P
C
N
I
L
C
G
T
E
K
Frog
Xenopus laevis
NP_001081114
911
104084
N542
R
K
R
D
P
P
S
N
I
L
C
G
I
E
K
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
A542
N
K
N
N
P
P
A
A
I
L
C
G
T
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
K548
P
P
L
W
F
H
Y
K
P
K
E
R
S
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
W575
D
K
E
N
P
P
R
W
L
Q
C
T
R
E
K
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
N542
P
S
F
Y
Q
V
T
N
N
S
K
E
R
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
N534
P
S
F
Y
Q
V
T
N
H
S
K
E
R
P
D
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
S571
S
E
V
A
P
P
A
S
I
L
E
F
G
S
K
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
G615
E
Y
I
E
L
G
G
G
E
K
L
Q
Y
E
K
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
80
N.A.
N.A.
73.3
60
60
N.A.
0
N.A.
N.A.
33.3
P-Site Similarity:
100
100
20
93.3
N.A.
100
86.6
N.A.
N.A.
86.6
80
86.6
N.A.
6.6
N.A.
N.A.
53.3
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
0
N.A.
N.A.
0
46.6
13.3
P-Site Similarity:
13.3
N.A.
N.A.
13.3
53.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
27
0
0
14
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
7
0
0
60
0
0
0
7
% C
% Asp:
7
0
0
14
0
0
0
0
7
0
0
0
0
0
14
% D
% Glu:
7
7
7
7
0
0
0
0
7
0
14
14
0
67
0
% E
% Phe:
0
0
14
0
7
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
0
0
7
0
7
7
7
0
0
0
60
7
7
0
% G
% His:
27
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
60
0
0
0
7
0
0
% I
% Lys:
0
34
40
0
0
0
0
7
0
14
14
0
0
0
74
% K
% Leu:
0
0
7
0
14
0
0
0
7
60
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
14
14
0
7
0
27
7
0
0
0
0
0
0
% N
% Pro:
20
7
0
0
60
67
0
0
7
0
0
0
0
14
7
% P
% Gln:
7
0
0
0
14
0
0
0
0
14
0
7
0
0
0
% Q
% Arg:
7
34
7
0
0
0
7
0
0
0
0
7
20
0
0
% R
% Ser:
14
14
0
14
0
0
40
34
0
14
0
0
7
14
0
% S
% Thr:
0
0
0
0
0
0
14
7
0
0
0
7
47
0
0
% T
% Val:
0
0
7
0
0
14
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
14
7
0
14
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _