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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
18.18
Human Site:
S830
Identified Species:
28.57
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S830
Y
A
V
I
N
D
L
S
T
K
N
E
G
T
R
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S830
Y
A
V
I
N
D
L
S
T
K
N
E
G
T
R
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
V565
Q
I
K
A
A
E
I
V
P
S
D
M
Y
K
T
Dog
Lupus familis
XP_542663
911
104163
S830
Y
A
V
I
N
D
L
S
T
K
I
E
G
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S830
Y
A
V
I
N
D
L
S
S
R
I
E
A
T
R
Rat
Rattus norvegicus
NP_001099565
911
104477
S830
Y
A
V
I
N
D
L
S
S
K
I
E
A
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
H835
N
K
P
S
T
K
I
H
G
T
R
L
S
I
R
Frog
Xenopus laevis
NP_001081114
911
104084
I833
I
N
D
P
T
T
R
I
N
T
S
S
L
N
I
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
I832
I
G
D
P
K
S
V
I
C
G
T
C
L
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
H841
N
A
F
F
Y
S
P
H
G
D
E
V
A
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
T868
L
V
I
G
E
E
D
T
H
I
K
D
C
S
L
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
L835
D
W
E
S
L
L
G
L
A
F
R
R
L
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
I826
E
E
E
A
L
L
G
I
M
A
K
R
L
M
L
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
F867
I
E
M
K
I
K
L
F
G
G
K
I
T
D
Q
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
N916
G
G
D
G
F
D
M
N
H
F
L
D
H
L
E
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
93.3
N.A.
73.3
80
N.A.
N.A.
6.6
0
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
33.3
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
0
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
0
N.A.
N.A.
0
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
14
7
0
0
0
7
7
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% C
% Asp:
7
0
20
0
0
40
7
0
0
7
7
14
0
14
0
% D
% Glu:
7
14
14
0
7
14
0
0
0
0
7
34
0
0
7
% E
% Phe:
0
0
7
7
7
0
0
7
0
14
0
0
0
0
0
% F
% Gly:
7
14
0
14
0
0
14
0
20
14
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
14
14
0
0
0
7
0
0
% H
% Ile:
20
7
7
34
7
0
14
20
0
7
20
7
0
7
7
% I
% Lys:
0
7
7
7
7
14
0
0
0
27
20
0
0
20
0
% K
% Leu:
7
0
0
0
14
14
40
7
0
0
7
7
27
7
27
% L
% Met:
0
0
7
0
0
0
7
0
7
0
0
7
0
7
0
% M
% Asn:
14
7
0
0
34
0
0
7
7
0
14
0
0
7
0
% N
% Pro:
0
0
7
14
0
0
7
0
7
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
7
14
14
0
0
40
% R
% Ser:
0
0
0
14
0
14
0
34
14
7
7
7
7
7
0
% S
% Thr:
0
0
0
0
14
7
0
7
20
14
7
0
7
34
14
% T
% Val:
0
7
34
0
0
0
7
7
0
0
0
7
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _