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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
12.42
Human Site:
S892
Identified Species:
19.52
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S892
K
F
K
I
L
K
E
S
W
V
T
D
S
I
D
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S892
K
F
K
I
L
K
E
S
W
V
T
D
S
I
D
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
Q624
V
G
G
D
D
G
P
Q
E
K
K
R
K
A
I
Dog
Lupus familis
XP_542663
911
104163
D892
K
F
K
I
L
Q
Q
D
W
V
T
E
S
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
S892
K
F
K
I
L
Q
E
S
W
V
S
D
S
V
D
Rat
Rattus norvegicus
NP_001099565
911
104477
R892
K
F
K
I
L
Q
E
R
W
V
I
D
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
W894
F
K
I
V
S
E
L
W
V
T
E
S
V
K
E
Frog
Xenopus laevis
NP_001081114
911
104084
S892
K
F
K
I
V
S
V
S
W
V
L
D
S
V
K
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
W891
F
K
I
V
H
E
S
W
V
T
D
S
I
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
A900
T
D
K
V
L
N
S
A
W
I
H
Q
C
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
E930
K
Q
H
V
V
T
S
E
W
V
R
D
C
I
Q
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
N1126
K
E
E
T
A
E
E
N
R
H
E
E
W
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
Q982
V
Q
R
R
R
G
K
Q
P
S
K
I
S
G
D
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
H926
V
A
P
E
W
V
D
H
S
I
N
E
N
C
Q
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
E1026
M
P
R
I
V
K
G
E
W
V
E
D
S
W
K
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
73.3
N.A.
80
73.3
N.A.
N.A.
0
60
0
N.A.
20
N.A.
N.A.
33.3
P-Site Similarity:
100
100
0
93.3
N.A.
100
86.6
N.A.
N.A.
20
73.3
13.3
N.A.
40
N.A.
N.A.
46.6
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
20
N.A.
N.A.
13.3
0
40
P-Site Similarity:
53.3
N.A.
N.A.
26.6
26.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
7
0
0
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
14
7
0
% C
% Asp:
0
7
0
7
7
0
7
7
0
0
7
47
0
0
47
% D
% Glu:
0
7
7
7
0
20
34
14
7
0
20
20
0
0
7
% E
% Phe:
14
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
14
7
0
0
0
0
0
0
7
0
% G
% His:
0
0
7
0
7
0
0
7
0
7
7
0
0
7
0
% H
% Ile:
0
0
14
47
0
0
0
0
0
14
7
7
7
27
7
% I
% Lys:
54
14
47
0
0
20
7
0
0
7
14
0
7
14
14
% K
% Leu:
0
0
0
0
40
0
7
0
0
0
7
0
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
7
0
7
0
0
% N
% Pro:
0
7
7
0
0
0
7
0
7
0
0
0
0
0
0
% P
% Gln:
0
14
0
0
0
20
7
14
0
0
0
7
0
0
14
% Q
% Arg:
0
0
14
7
7
0
0
7
7
0
7
7
0
0
7
% R
% Ser:
0
0
0
0
7
7
20
27
7
7
7
14
54
0
0
% S
% Thr:
7
0
0
7
0
7
0
0
0
14
20
0
0
0
0
% T
% Val:
20
0
0
27
20
7
7
0
14
54
0
0
7
20
0
% V
% Trp:
0
0
0
0
7
0
0
14
60
0
0
0
7
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _